The pursuit of optimal health and longevity is a long-standing human aspiration [1, 2].
Advances in public health policies and population medicine have significantly extended life …

As human life expectancy continues to increase and the birth rate continues to decline, the
phenomenon of aging is becoming more prominent worldwide. Therefore, addressing the …

Achieving healthy human longevity: A global grand challenge | Science Translational Medicine
news careers commentary Journals Science Science brought to you byGoogle Indexer Log in …

In recent years, there has been a paradigm shift with regards to ageing, challenging its
traditional perception as an inevitable and natural process. Researchers have collectively …

Aging process is associated with numerous intrinsic and extrinsic factors that contribute to
the adipose tissue accumulation, atherosclerosis, immune system failures, bone fragility …

Stem cells, a special subset of cells derived from embryo or adult tissues, are known to
present the characteristics of self-renewal, multiple lineages of differentiation, high plastic …

Life expectancy has increased by three decades since the mid-twentieth century. Parallel
healthspan expansion has however not followed, largely impeded by the pandemic of …

Self-renewal and multilineage differentiation of stem cells are keys to the lifelong
homeostatic maintenance of tissues and organs. Hematopoietic aging, characterized by …

Aging is a progressive and cumulative deterioration of the physiological functioning of life.
Over the last several decades, an increasing understanding of the causes of aging has been …

Adult stem cells have taken center stage in current research related to regenerative
medicine and pharmacogenomic studies seeking new therapeutic interventions. As we learn …