Background Variable responses to the Hepatitis B Virus (HBV) vaccine have recently been
reported as strongly dependent on genetic causes. Yet, the details on such mechanisms of …

Background & aim Hepatitis B virus (HBV) can be transmitted to infants, and is related to
infants' later disease risk. Epigenetic change (such as DNA methylation) may be mechanism …

The etiology of early‐onset hepatocellular carcinoma (HCC) among hepatitis B virus (HBV)
carriers remains unclear. DNA methylation levels in peripheral leukocytes have been …

Individuals fail to elicit protective antibody after hepatitis B vaccination remain at risk for
hepatitis B virus infection. Analysis of the transcriptome of peripheral blood mononuclear …

Viral infections are able to modify the host's cellular programs, with DNA methylation being a
biological intermediate in this process. The extent to which viral infections deregulate gene …

Abstract Background Hepatitis B virus (HBV)-related liver disease induces liver damage by
hepatic immune and inflammatory response. The association between aberrant peripheral …

The natural course of chronic hepatitis B (CHB) infection and treatment response are
determined mainly by the genomic characteristics of the individual. We investigated liver …

Background An important model of hepatocellular carcinoma (HCC) that has been
described in southeast Asia includes the transition from chronic hepatitis B infection (CHB) …

Background Vaccination against hepatitis B virus infection (HBV) is safe and effective;
however, vaccine-induced antibody level wanes over time. Peak vaccine-induced anti-HBs …

Chronic hepatitis B virus (HBV) infection is still a major health problem worldwide. Recently,
a great number of genetic studies based on single nucleotide polymorphisms (SNPs) and …