Many fungal pathogens undergo a yeast-hyphal transition during their pathogenic
development that requires rearrangement of the cytoskeleton, followed by directed …

Growth of most eukaryotic cells requires directed transport along microtubules (MTs) that are
nucleated at nuclear-associated microtubule organizing centers (MTOCs), such as the …

Fungal pathogenicity often involves a yeast-to-hypha transition, but the structural basis for
this dimorphism is largely unknown. Here we analyze the role of the cytoskeleton in early …

Pathogenic development of the corn smut fungus Ustilago maydis depends on the ability of
the hypha to grow invasively. Extended hyphal growth and mitosis require microtubules, as …

Microtubules (MTs) are often organized by a nucleus-associated MT organizing center
(MTOC). In addition, in neurons and epithelial cells, motor-based transport of assembled …

Ustilago maydis is a dimorphic Basidiomycete fungus with a yeast-like form and a hyphal
form. Here we present a comprehensive analysis of bud formation and the actin and …

Ustilago maydis, a Basidiomycete fungus that infects maize, exhibits two basic
morphologies, a yeast-like and a filamentous form. The yeast-like cell is elongated, divides …

The microtubule cytoskeleton supports cellular morphogenesis and polar growth, but the
underlying mechanisms are not understood. In a screen for morphology mutants defective in …

We have recently discovered that the mipA gene of A. nidulans encodes y-tubulin, a new
member of the tubulin superfamily. To determine the function of y-tubulin in vivo, we have …

The endoplasmic reticulum (ER) of most vertebrate cells is spread out by kinesin-dependent
transport along microtubules, whereas studies in Saccharomyces cerevisiae indicated that …