Emerging roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of neural stem cells proliferation and differentiation

AM Cimini, MP Cerù - Stem cell reviews, 2008 - Springer
The molecular mechanisms controlling the specification of neural cell fates have been the
focus of intense research in recent years. Neural precursor cells (NPCs) sequentially …

[Retracted] PPARs Expression in Adult Mouse Neural Stem Cells: Modulation of PPARs during Astroglial Differentiaton of NSC

A Cimini, L Cristiano, E Benedetti… - PPAR …, 2007 - Wiley Online Library
PPAR isotypes are involved in the regulation of cell proliferation, death, and differentiation,
with different roles and mechanisms depending on the specific isotype and ligand and on …

[HTML][HTML] PPARβ/δ and PPARγ maintain undifferentiated phenotypes of mouse adult neural precursor cells from the subventricular zone

C Bernal, C Araya, V Palma… - Frontiers in Cellular …, 2015 - frontiersin.org
The subventricular zone (SVZ) is one of the main niches of neural stem cells in the adult
mammalian brain. Stem and precursor cells in this region are the source for neurogenesis …

[HTML][HTML] PPARs and energy metabolism adaptation during neurogenesis and neuronal maturation

M D'Angelo, A Antonosante, V Castelli… - International Journal of …, 2018 - mdpi.com
Peroxisome proliferator activated receptors (PPARs) are a class of ligand-activated
transcription factors, belonging to the superfamily of receptors for steroid and thyroid …

[HTML][HTML] PPARγ agonists promote oligodendrocyte differentiation of neural stem cells by modulating stemness and differentiation genes

S Kanakasabai, E Pestereva, W Chearwae, SK Gupta… - PloS one, 2012 - journals.plos.org
Neural stem cells (NSCs) are a small population of resident cells that can grow, migrate and
differentiate into neuro-glial cells in the central nervous system (CNS). Peroxisome …

[HTML][HTML] Peroxisome proliferator-activated receptor γ-mediated regulation of neural stem cell proliferation and differentiation

K Wada, A Nakajima, K Katayama, C Kudo… - Journal of Biological …, 2006 - ASBMB
Peroxisome proliferator-activated receptor γ (PPARγ) plays an important role in insulin
sensitivity, tissue homeostasis, and regulating cellular functions. We found high-level …

The influence of peroxisome proliferator-activated receptor γ1 during differentiation of mouse embryonic stem cells to neural cells

A Ghoochani, K Shabani, M Peymani, K Ghaedi… - Differentiation, 2012 - Elsevier
Peroxisome proliferator activated receptor γ, belongs to PPARs, which exerts various
metabolic functions including differentiation process. To testify the importance of PPARγ in …

Signal transduction pathways involved in PPARβ/δ‐induced neuronal differentiation

B D'Angelo, E Benedetti, S Di Loreto… - Journal of cellular …, 2011 - Wiley Online Library
Neuroblastomas are pediatric tumors originating from neuroblasts in the developing
peripheral nervous system. The neurotrophin brain‐derived neurotrophic factor (BDNF) is a …

Expression and function of PPARs in cancer stem cells

Y Zhang, X Zhang, J Wang, Y Shen… - Current Stem Cell …, 2016 - ingentaconnect.com
Cancer stem cells (CSCs) are cancer cells with characteristics of stem cells, especially the
ability to arise to all types of cell in a particular cancer tissue. With the capacity to generate …

Peroxisome proliferator‐activated receptor γ ligands regulate neural stem cell proliferation and differentiation in vitro and in vivo

JA Morales‐Garcia, R Luna‐Medina, C Alfaro‐Cervello… - Glia, 2011 - Wiley Online Library
Peroxisome proliferator‐activated receptor gamma (PPARγ) belongs to a family of ligand‐
activated nuclear receptors and its ligands are known to control many physiological and …