Combination drugs have been used for several diseases for many years since they produce
better therapeutic effects. However, it is still a challenge to discover candidates to form a …

Recently, scary viral pneumonia is known as (COVID-19) has swept the whole world. The
new virus strain designated as SARS-CoV-2 belonging to the coronavirus family. Although …

Background: The COVID-19 pandemic emerged at the end of 2019 in China and spread
rapidly all over the world. Scientists strive to find virus-specific antivirals against COVID-19 …

This work aimed at evaluating the inhibitory effect of ten natural bioactive compounds (1–10)
as potential inhibitors of SARS-CoV-2-3CL main protease (PDB ID: 6LU7) and SARS-CoV …

Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative
agent of the pandemic COVID-19 disease that affects human respiratory function. Despite …

The 3CLpro main protease and the RDB spike (s) protein of SARS-CoV-2 are critical targets
in the treatment of coronavirus 19 disease (COVID-19), as they are responsible for the …

The emergence of the COVID-19 situation has become a global issue due to the lack of
effective antiviral drugs for treatment. Flavonoids are a class of plant secondary metabolites …

The newly occurred SARS-CoV-2 caused a leading pandemic of coronavirus disease
(COVID-19). Up to now it has infected more than one hundred sixty million and killed more …

The SARS-CoV-2 is the causative agent of COVID-19 pandemic that is causing a global
health emergency. The lack of targeted therapeutics and limited treatment options have …

Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is highly
pathogenic to humans and has created health care threats worldwide. This urgent situation …