Detection and separation of single-stranded dna fragments using solid-state nanopores

L Zhan, Y Zhang, W Si, J Sha… - The Journal of Physical …, 2021 - ACS Publications
Many biological assays require effectively and sensitively sorting DNA fragments. Here, we
demonstrate a solid-state nanopore platform for label-free detection and separation of short …

Unraveling single-stranded DNA in a solid-state nanopore

SW Kowalczyk, MW Tuijtel, SP Donkers, C Dekker - Nano letters, 2010 - ACS Publications
Solid-state nanopores are an emerging class of single-molecule sensors. Whereas most
studies so far focused on double-stranded DNA (dsDNA) molecules, exploration of single …

Mechanical trapping of DNA in a double-nanopore system

S Pud, SH Chao, M Belkin, D Verschueren… - Nano …, 2016 - ACS Publications
Nanopores have become ubiquitous components of systems for single-molecule
manipulation and detection, in particular DNA sequencing where electric field driven …

Voltage-driven translocation of DNA through a high throughput conical solid-state nanopore

Q Liu, H Wu, L Wu, X Xie, J Kong, X Ye, L Liu - 2012 - journals.plos.org
Nanopores have become an important tool for molecule detection at single molecular level.
With the development of fabrication technology, synthesized solid-state membranes are …

Solid-state nanopore channels with DNA selectivity

SM Iqbal, D Akin, R Bashir - Nature nanotechnology, 2007 - nature.com
Solid-state nanopores have emerged as possible candidates for next-generation DNA
sequencing devices. In such a device, the DNA sequence would be determined by …

Controlling DNA translocation through solid-state nanopores

Z Yuan, Y Liu, M Dai, X Yi, C Wang - Nanoscale research letters, 2020 - Springer
Compared with the status of bio-nanopores, there are still several challenges that need to be
overcome before solid-state nanopores can be applied in commercial DNA sequencing …

Slowing DNA translocation in a solid-state nanopore

D Fologea, J Uplinger, B Thomas, DS McNabb, J Li - Nano letters, 2005 - ACS Publications
Reducing a DNA molecule's translocation speed in a solid-state nanopore is a key step
toward rapid single molecule identification. Here we demonstrate that DNA translocation …

Fast fabrication of solid-state nanopores for DNA molecule analysis

Y Zhang, D Ma, Z Gu, L Zhan, J Sha - Nanomaterials, 2021 - mdpi.com
Solid-state nanopores have been developed as a prominent tool for single molecule
analysis in versatile applications. Although controlled dielectric breakdown (CDB) is the …

Capture and translocation characteristics of short branched DNA labels in solid-state nanopores

P Karau, V Tabard-Cossa - ACS sensors, 2018 - ACS Publications
The challenge when employing solid-state nanopores as single-molecule sensors in a given
assay is the specificity of the ionic current signal during the translocation of target molecules …

Nanopore-based single-molecule DNA analysis

K Healy - 2007 - Taylor & Francis
Nanopore-based DNA analysis is a single-molecule technique with revolutionary potential. It
promises to carry out a range of analyses, orders of magnitude faster than current methods …