Drug repositioning is an innovative approach to identify new therapeutic indications for existing drugs. Drug repositioning offers the promise of reducing drug development …
H Wu, J Huang, Y Zhong, Q Huang - PloS one, 2017 - journals.plos.org
Computational drug repositioning has been proved as an effective approach to develop new drug uses. However, currently existing strategies strongly rely on drug response gene …
E Kim, A Choi, H Nam - BMC bioinformatics, 2019 - Springer
Background Drug repositioning, also known as drug repurposing, defines new indications for existing drugs and can be used as an alternative to drug development. In recent years …
E Jadamba, M Shin - BioMed research international, 2016 - Wiley Online Library
Drug repositioning offers new clinical indications for old drugs. Recently, many computational approaches have been developed to repurpose marketed drugs in human …
Drug repositioning can drastically decrease the cost and duration taken by traditional drug research and development while avoiding the occurrence of unforeseen adverse events …
Background Drug repositioning is a cost-efficient and time-saving process to drug development compared to traditional techniques. A systematic method to drug repositioning …
Background The process of drug discovery and development is time-consuming and costly, and the probability of success is low. Therefore, there is rising interest in repositioning …
Background Given the costly and time consuming process and high attrition rates in drug discovery and development, drug repositioning or drug repurposing is considered as a …
Traditionally, most drugs have been discovered using phenotypic or target‐based screens. Subsequently, their indications are often expanded on the basis of clinical observations …