Distribution of microRNA biomarker candidates in solid tissues and body fluids

T Fehlmann, N Ludwig, C Backes, E Meese… - RNA biology, 2016 - Taylor & Francis
Small non-coding RNAs, especially microRNAs, are discussed as promising biomarkers for
a substantial number of human pathologies. A broad understanding in which solid tissues …

Small RNAs have a large impact: circulating microRNAs as biomarkers for human diseases

M Weiland, XH Gao, L Zhou, QS Mi - RNA biology, 2012 - Taylor & Francis
The highly conserved RNAs, microRNAs (miRNAs), are a class of small single stranded
noncoding RNAs that function through translational repression of specific target mRNAs …

Characterization of microRNA expression profiles in normal human tissues

Y Liang, D Ridzon, L Wong, C Chen - BMC genomics, 2007 - Springer
Background Measuring the quantity of miRNAs in tissues of different physiological and
pathological conditions is an important first step to investigate the functions of miRNAs …

What is normal? Next generation sequencing-driven analysis of the human circulating miRNAOme

DP Tonge, TW Gant - BMC molecular biology, 2016 - Springer
Background MicroRNAs (miRNAs) are short non-protein-coding RNA species that have a
regulatory function in modulating protein translation and degradation of specific mRNAs …

Extracellular microRNA: a new source of biomarkers

A Etheridge, I Lee, L Hood, D Galas, K Wang - … Research/Fundamental and …, 2011 - Elsevier
MicroRNAs (miRNAs) are a recently discovered class of small, non-coding RNAs that
regulate protein levels post-transcriptionally. miRNAs play important regulatory roles in …

Issues and prospects of microRNA-based biomarkers in blood and other body fluids

JR Chevillet, I Lee, HA Briggs, Y He, K Wang - Molecules, 2014 - mdpi.com
Cell-free circulating microRNAs (miRNAs) in the blood are good diagnostic biomarker
candidates for various physiopathological conditions, including cancer, neurodegeneration …

Evaluation of two commercial global miRNA expression profiling platforms for detection of less abundant miRNAs

SG Jensen, P Lamy, MH Rasmussen, MS Ostenfeld… - BMC genomics, 2011 - Springer
Background microRNAs (miRNA) are short, endogenous transcripts that negatively regulate
the expression of specific mRNA targets. miRNAs are found both in tissues and body fluids …

Comparison of different extraction techniques to profile microRNAs from human sera and peripheral blood mononuclear cells

M Monleau, S Bonnel, T Gostan, D Blanchard… - BMC genomics, 2014 - Springer
Background microRNAs (miRNAs) play crucial roles in major biological processes and their
deregulations are often associated with human malignancies. As such, they represent …

The microRNA spectrum in 12 body fluids

JA Weber, DH Baxter, S Zhang, DY Huang… - Clinical …, 2010 - academic.oup.com
BACKGROUND MicroRNAs (miRNAs) are small, noncoding RNAs that play an important
role in regulating various biological processes through their interaction with cellular …

MicroRNAs as biomarkers for clinical studies

IP Pogribny - Experimental Biology and Medicine, 2018 - journals.sagepub.com
The development of better diagnostic and prognostic non-invasive biomarkers holds an
enormous potential to improve the ability to diagnose and individualize treatment of a great …