Grader variability and the importance of reference standards for evaluating machine learning models for diabetic retinopathy

J Krause, V Gulshan, E Rahimy, P Karth, K Widner… - Ophthalmology, 2018 - Elsevier
Purpose Use adjudication to quantify errors in diabetic retinopathy (DR) grading based on
individual graders and majority decision, and to train an improved automated algorithm for …

[HTML][HTML] Using a deep learning algorithm and integrated gradients explanation to assist grading for diabetic retinopathy

R Sayres, A Taly, E Rahimy, K Blumer, D Coz… - Ophthalmology, 2019 - Elsevier
Purpose To understand the impact of deep learning diabetic retinopathy (DR) algorithms on
physician readers in computer-assisted settings. Design Evaluation of diagnostic …

Deep learning versus human graders for classifying diabetic retinopathy severity in a nationwide screening program

P Ruamviboonsuk, J Krause, P Chotcomwongse… - NPJ digital …, 2019 - nature.com
Deep learning algorithms have been used to detect diabetic retinopathy (DR) with specialist-
level accuracy. This study aims to validate one such algorithm on a large-scale clinical …

DR| GRADUATE: Uncertainty-aware deep learning-based diabetic retinopathy grading in eye fundus images

T Araújo, G Aresta, L Mendonça, S Penas, C Maia… - Medical Image …, 2020 - Elsevier
Diabetic retinopathy (DR) grading is crucial in determining the adequate treatment and
follow up of patient, but the screening process can be tiresome and prone to errors. Deep …

Evaluation of artificial intelligence–based grading of diabetic retinopathy in primary care

Y Kanagasingam, D Xiao, J Vignarajan… - JAMA network …, 2018 - jamanetwork.com
Importance There has been wide interest in using artificial intelligence (AI)–based grading of
retinal images to identify diabetic retinopathy, but such a system has never been deployed …

Deep learning–based algorithms in screening of diabetic retinopathy: a systematic review of diagnostic performance

KB Nielsen, ML Lautrup, JKH Andersen… - Ophthalmology …, 2019 - Elsevier
Topic Diagnostic performance of deep learning–based algorithms in screening patients with
diabetes for diabetic retinopathy (DR). The algorithms were compared with the current gold …

[HTML][HTML] Automated diabetic retinopathy image assessment software: diagnostic accuracy and cost-effectiveness compared with human graders

A Tufail, C Rudisill, C Egan, VV Kapetanakis… - Ophthalmology, 2017 - Elsevier
Objective With the increasing prevalence of diabetes, annual screening for diabetic
retinopathy (DR) by expert human grading of retinal images is challenging. Automated DR …

Performance of a deep-learning algorithm vs manual grading for detecting diabetic retinopathy in India

V Gulshan, RP Rajan, K Widner, D Wu… - JAMA …, 2019 - jamanetwork.com
Importance More than 60 million people in India have diabetes and are at risk for diabetic
retinopathy (DR), a vision-threatening disease. Automated interpretation of retinal fundus …

Multicenter, head-to-head, real-world validation study of seven automated artificial intelligence diabetic retinopathy screening systems

AY Lee, RT Yanagihara, CS Lee, M Blazes… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVE With rising global prevalence of diabetic retinopathy (DR), automated DR
screening is needed for primary care settings. Two automated artificial intelligence (AI) …

Artificial Intelligence and Diabetic Retinopathy: AI Framework, prospective studies, head-to-head validation, and cost-effectiveness

AE Rajesh, OQ Davidson, CS Lee, AY Lee - Diabetes care, 2023 - Am Diabetes Assoc
Current guidelines recommend that individuals with diabetes receive yearly eye exams for
detection of referable diabetic retinopathy (DR), one of the leading causes of new-onset …