Neurotoxic effects of aluminium exposure as a potential risk factor for Alzheimer's disease

M Dey, RK Singh - Pharmacological Reports, 2022 - Springer
Aluminium is one of the most widely distributed elements of the Earth's crust. Its routine use
has resulted in excessive human exposure and due to the potential neurotoxic effects has …

Multifaceted effects of aluminium in neurodegenerative diseases: A review

S Maya, T Prakash, KD Madhu, D Goli - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Aluminium (Al) is the most common metal and widely distributed in our environment. Al was
first isolated as an element in 1827, and its use began only after 1886. Al is widely used for …

Role of aluminum exposure on Alzheimer's disease and related glycogen synthase kinase pathway

S Sanajou, P Erkekoğlu, G Şahin… - Drug and chemical …, 2023 - Taylor & Francis
Aluminum (Al) is an environmentally abundant metal that is not essential for life. There is
considerable evidence that Al as a neurotoxic xenobiotic may play a role in the …

Exposure to aluminum in daily life and Alzheimer's disease

J Nie - Neurotoxicity of Aluminum, 2018 - Springer
Aluminum is the third most abundant element on the earth's crust and has been considered
a constituent of rather inert minerals. Therefore, it has often been regarded as not having a …

Aluminium in Alzheimer's disease: are we still at a crossroad?

VB Gupta, S Anitha, ML Hegde, L Zecca… - Cellular and Molecular …, 2005 - Springer
Aluminium, an environmentally abundant non-redox trivalent cation has long been
implicated in the pathogenesis of Alzheimer's disease (AD). However, the definite …

Aluminum and human health: its intake, bioavailability and neurotoxicity

M Kawahara, K Konoha, T Nagata… - Biomedical research on …, 2007 - jstage.jst.go.jp
Aluminum is the most abundant metal in the earth's crust. However, it is not essential for life.
Owing to its specific chemical properties, aluminum inhibits more than 200 biologically …

Oxidative stress and mitochondrial dysfunction in aluminium neurotoxicity and its amelioration: a review

V Kumar, KD Gill - Neurotoxicology, 2014 - Elsevier
Aluminium is light weight and toxic metal present ubiquitously on earth which has gained
considerable attention due to its neurotoxic effects. The widespread use of products made …

Chronic oral exposure of aluminum chloride in rat modulates molecular and functional neurotoxic markers relevant to Alzheimer's disease

M Dey, RK Singh - Toxicology Mechanisms and Methods, 2022 - Taylor & Francis
Aluminum is an environmentally abundant potential neurotoxic agent that may result in
oxidative damage to a range of cellular biomarkers. The potential sources of aluminum …

Aluminium-induced electrophysiological, biochemical and cognitive modifications in the hippocampus of aging rats

P Sethi, A Jyoti, R Singh, E Hussain, D Sharma - Neurotoxicology, 2008 - Elsevier
Aluminium (Al) is the most abundant metal known for its neurotoxicity in humans. It gains
easy access to the central nervous system under normal physiological conditions and …

Molecular toxicity of aluminium in relation to neurodegeneration

P Vasudevaraju, M Govindaraju… - Indian Journal of …, 2008 - journals.lww.com
Exposure to high levels of aluminium (Al) leads to neurofibrillary degeneration and that Al
concentration is increased in degenerating neurons in Alzheimer′ s disease (AD) …