BACKGROUND:: Schizophrenia is believed to result from abnormal functional integration of
neural processes thought to arise from aberrant brain connectivity. However, evidence for …

Schizophrenia—a severe psychiatric condition characterized by hallucinations, delusions,
loss of initiative and cognitive function—is hypothesized to result from abnormal anatomical …

BACKGROUND: Schizophrenia is hypothesized to involve disordered connectivity between
brain regions. Currently, there are no direct measures of brain connectivity; functional and …

Neuroimaging studies have demonstrated that the phenomenology of schizophrenia maps
onto diffuse alterations in large-scale functional and structural brain networks. However, the …

Schizophrenia is a severe psychiatric disorder with multi-factorial characteristics. A number
of findings have shown disrupted synaptic connectivity in schizophrenia patients and …

Disturbances in “functional connectivity” have been proposed as a major pathophysiological
mechanism for schizophrenia, and in particular, for cognitive disorganization. Detection and …

Schizophrenia (SZ) and bipolar disorder (BD) are often conceptualized as “disconnection
syndromes,” with substantial evidence of abnormalities in deep white matter tracts, forming …

Schizophrenia is frequently characterized as a disorder of brain connectivity. Neuroimaging
has played a central role in supporting this view, with nearly two decades of research …

A wide range of neuropathological abnormalities have been detected in schizophrenia
sufferers, and emerging evidence points to neural substrates of connectivity as having a key …

Objective The pathophysiology of chronic schizophrenia may reflect long term brain
changes related to the disorder. The effect of chronicity on intrinsic functional connectivity …