A state-of-the-art of functional scaffolds for 3D nervous tissue regeneration

MG Tupone, M d'Angelo, V Castelli… - … in Bioengineering and …, 2021 - frontiersin.org
Exploring and developing multifunctional intelligent biomaterials is crucial to improve next-
generation therapies in tissue engineering and regenerative medicine. Recent findings …

Interfacing cells with microengineered scaffolds for neural tissue reconstruction

A Accardo, C Cirillo, S Lionnet, C Vieu… - Brain Research Bulletin, 2019 - Elsevier
The development of cellular microenvironments suitable for neural tissue engineering
purposes involves a plethora of research fields ranging from cell biology to biochemistry …

Scaffolds for 3D in vitro culture of neural lineage cells

AR Murphy, A Laslett, CM O'Brien, NR Cameron - Acta Biomaterialia, 2017 - Elsevier
Understanding how neurodegenerative disorders develop is not only a key challenge for
researchers but also for the wider society, given the rapidly aging populations in developed …

Novel advancements in three-dimensional neural tissue engineering and regenerative medicine

RJ McMurtrey - Neural Regeneration Research, 2015 - journals.lww.com
Neurological diseases and injuries present some of the greatest challenges in modern
medicine, often causing irreversible and lifelong burdens in the people whom they afflict …

3D scaffolds for brain tissue regeneration: architectural challenges

GD Mahumane, P Kumar, LC du Toit… - Biomaterials …, 2018 - pubs.rsc.org
Biomaterials are being utilized to engender biomimetic, pro-regenerative constructs in the
form of 3D scaffolds to augment functional neural tissue (brain tissue) repair and …

Advances in tissue engineering and innovative fabrication techniques for 3-D-structures: translational applications in neurodegenerative diseases

F Rey, B Barzaghini, A Nardini, M Bordoni, GV Zuccotti… - Cells, 2020 - mdpi.com
In the field of regenerative medicine applied to neurodegenerative diseases, one of the most
important challenges is the obtainment of innovative scaffolds aimed at improving the …

[HTML][HTML] Bidirectional cell-matrix interaction dictates neuronal network formation in a brain-mimetic 3D scaffold

S Samanta, L Ylä-Outinen, VK Rangasami, S Narkilahti… - Acta Biomaterialia, 2022 - Elsevier
Human pluripotent stem cells (hPSC) derived neurons are emerging as a powerful tool for
studying neurobiology, disease pathology, and modeling. Due to the lack of platforms …

Biomimetic materials and their utility in modeling the 3-dimensional neural environment

A Cembran, KF Bruggeman, RJ Williams, CL Parish… - Iscience, 2020 - cell.com
The brain is a complex 3-dimensional structure, the organization of which provides a local
environment that directly influences the survival, proliferation, differentiation, migration, and …

Neurorepair and regeneration of the brain: a decade of bioscaffolds and engineered microtissue

LN Zamproni, MTVV Mundim… - Frontiers in cell and …, 2021 - frontiersin.org
Repairing the human brain remains a challenge, despite the advances in the knowledge of
inflammatory response to injuries and the discovery of adult neurogenesis. After brain injury …

Utilizing stem cells for three-dimensional neural tissue engineering

S Knowlton, Y Cho, XJ Li, A Khademhosseini… - Biomaterials …, 2016 - pubs.rsc.org
Three-dimensional neural tissue engineering has made great strides in developing neural
disease models and replacement tissues for patients. However, the need for biomimetic …