[HTML][HTML] Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions

JS Xiang, JR Mueller, EC Luo, BA Yee… - Research …, 2022 - ncbi.nlm.nih.gov
The COVID-19 pandemic is caused by severe acute respiratory syndrome-coronavirus-2
(SARS-CoV-2). The betacoronvirus has a positive sense RNA genome which encodes for …

[HTML][HTML] Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions

RA Flynn, JA Belk, Y Qi, Y Yasumoto, J Wei… - Cell, 2021 - cell.com
SARS-CoV-2 is the cause of a pandemic with growing global mortality. Using
comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) …

Characterization and functional interrogation of the SARS-CoV-2 RNA interactome

A Labeau, L Fery-Simonian, A Lefevre-Utile… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the COVID-19 pandemic, which has led to a devastating global health crisis. The emergence …

The SARS-CoV-2 RNA Interactome

S Lee, Y Lee, Y Choi, A Son, Y Park, KM Lee, J Kim… - Molecular Cell, 2021 - cell.com
SARS-CoV-2 is an RNA virus whose success as a pathogen relies on its abilities to
repurpose host RNA-binding proteins (RBPs) and to evade antiviral RBPs. To uncover the …

Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection

W Kamel, M Noerenberg, B Cerikan, H Chen… - Molecular cell, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to …

RNA–protein interactomes as invaluable resources to study RNA viruses: Insights from SARS CoV‐2 studies

M Koliński, E Kałużna… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Understanding the molecular mechanisms of severe respiratory syndrome coronavirus 2
(SARS‐CoV‐2) infection is essential for the successful development of therapeutic …

High-sensitivity profiling of SARS-CoV-2 noncoding region–host protein interactome reveals the potential regulatory role of negative-sense viral RNA

L Jiang, M Xiao, QQ Liao, L Zheng, C Li, Y Liu, B Yang… - Msystems, 2023 - Am Soc Microbiol
ABSTRACT A deep understanding of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2)–host interactions is crucial to developing effective therapeutics and …

[HTML][HTML] Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection

RA Flynn, JA Belk, Y Qi, Y Yasumoto, CO Schmitz… - Biorxiv, 2020 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a pandemic
with growing global mortality. There is an urgent need to understand the molecular …

The SARS-CoV-2 RNA–protein interactome in infected human cells

N Schmidt, CA Lareau, H Keshishian, S Ganskih… - Nature …, 2021 - nature.com
Characterizing the interactions that SARS-CoV-2 viral RNAs make with host cell proteins
during infection can improve our understanding of viral RNA functions and the host innate …

[HTML][HTML] SARS-CoV-2 disrupts splicing, translation, and protein trafficking to suppress host defenses

AK Banerjee, MR Blanco, EA Bruce, DD Honson… - Cell, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently identified
coronavirus that causes the respiratory disease known as coronavirus disease 2019 (COVID …