Reperfusion therapy in acute ischemic stroke: dawn of a new era?

S Bhaskar, P Stanwell, D Cordato, J Attia, C Levi - BMC neurology, 2018 - Springer
Following the success of recent endovascular trials, endovascular therapy has emerged as
an exciting addition to the arsenal of clinical management of patients with acute ischemic …

Endovascular approaches to acute stroke, part 2: a comprehensive review of studies and trials

RG Nogueira, AJ Yoo… - American journal of …, 2009 - Am Soc Neuroradiology
Reperfusion remains the mainstay of acute ischemic stroke treatment. Endovascular therapy
has become a promising alternative for patients who are ineligible for or have failed …

From “time is brain” to “imaging is brain”: a paradigm shift in the management of acute ischemic stroke

J Puig, J Shankar, D Liebeskind… - Journal of …, 2020 - Wiley Online Library
Arterial recanalization to restore the blood supply and limit the brain damage is the primary
goal in the management of acute ischemic stroke (AIS). Since the publication of pivotal …

Treatment for ischemic stroke: From thrombolysis to thrombectomy and remaining challenges

T Leng, ZG Xiong - Brain circulation, 2019 - journals.lww.com
Stroke is a leading cause of death and long-term disabilities. Despite decades of extensive
efforts in search of brain injury mechanisms and therapeutic interventions, pharmacological …

Extending the time window for endovascular and pharmacological reperfusion

N Henninger, M Fisher - Translational stroke research, 2016 - Springer
Pharmacological and device-induced reperfusion therapies have demonstrated increasingly
positive outcomes regarding both reperfusion efficacy and 90-day functional outcomes after …

Endovascular treatment of acute ischemic stroke

GS Silva, RG Nogueira - Continuum: Lifelong Learning in …, 2020 - journals.lww.com
PURPOSE OF REVIEW This article reviews the actual indications for mechanical
thrombectomy in patients with acute ischemic stroke and how the opportunities for …

Extending reperfusion therapy for acute ischemic stroke: emerging pharmacological, mechanical, and imaging strategies

CA Molina, JL Saver - Stroke, 2005 - Am Heart Assoc
Background and Purpose—Reperfusion is the most beneficial of all therapeutic strategies
for acute ischemic stroke. However, the standard cerebral reperfusion treatment of the first …

Acute ischemic stroke intervention

P Khandelwal, DR Yavagal, RL Sacco - Journal of the American College of …, 2016 - jacc.org
Acute ischemic stroke (AIS) is the leading cause of disability worldwide and among the
leading causes of mortality. Although intravenous tissue plasminogen activator (IV-rtPA) was …

Acute stroke therapy: a review

T Peisker, B Koznar, I Stetkarova, P Widimsky - Trends in cardiovascular …, 2017 - Elsevier
This review summarizes the modern early diagnosis and acute phase treatment of acute
stroke. The guidelines for treatment of acute ischemic stroke underwent major changes in …

[HTML][HTML] Emerging therapies in acute ischemic stroke

N Liaw, D Liebeskind - F1000Research, 2020 - ncbi.nlm.nih.gov
Thrombolysis and mechanical thrombectomy have revolutionized the care of patients with
acute ischemic stroke. The number of patients who can benefit from these treatments …