Statin use for the primary prevention of cardiovascular disease in adults: US Preventive Services Task Force recommendation statement

K Bibbins-Domingo, DC Grossman, SJ Curry… - Jama, 2016 - jamanetwork.com
Importance Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in
the United States, accounting for 1 of every 3 deaths among adults. Objective To update the …

Statin use for the primary prevention of cardiovascular disease in adults: US Preventive Services Task Force recommendation statement

CM Mangione, MJ Barry, WK Nicholson, M Cabana… - Jama, 2022 - jamanetwork.com
Importance Cardiovascular disease (CVD) is the leading cause of morbidity and death in the
US and is the cause of more than 1 of every 4 deaths. Coronary heart disease is the single …

Statins for prevention of cardiovascular disease in adults: evidence report and systematic review for the US Preventive Services Task Force

R Chou, T Dana, I Blazina, M Daeges, TL Jeanne - Jama, 2016 - jamanetwork.com
Importance Cardiovascular disease (CVD), the leading cause of mortality and morbidity in
the United States, may be potentially preventable with statin therapy. Objective To …

Statins for primary prevention of cardiovascular disease: review of evidence and recommendations for clinical practice

DS Kazi, JM Penko, K Bibbins-Domingo - Medical Clinics, 2017 - medical.theclinics.com
Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality in the
United States despite steady improvements over the past several decades. 1 High serum …

Statin use for the primary prevention of cardiovascular disease in adults: updated evidence report and systematic review for the US Preventive Services Task Force

R Chou, A Cantor, T Dana, J Wagner, AY Ahmed, R Fu… - Jama, 2022 - jamanetwork.com
Importance A 2016 review for the US Preventive Services Task Force (USPSTF) found use
of statins for primary prevention of cardiovascular disease (CVD) was associated with …

Finding the balance between benefits and harms when using statins for primary prevention of cardiovascular disease: a modeling study

HG Yebyo, HE Aschmann, MA Puhan - Annals of internal medicine, 2019 - acpjournals.org
Background: Many guidelines use expected risk for cardiovascular disease (CVD) during
the next 10 years as a basis for recommendations on use of statins for primary prevention of …

Effect of statin treatment vs usual care on primary cardiovascular prevention among older adults: the ALLHAT-LLT randomized clinical trial

BH Han, D Sutin, JD Williamson, BR Davis… - JAMA internal …, 2017 - jamanetwork.com
Importance While statin therapy for primary cardiovascular prevention has been associated
with reductions in cardiovascular morbidity, the effect on all-cause mortality has been …

Individualized statin benefit for determining statin eligibility in the primary prevention of cardiovascular disease

G Thanassoulis, K Williams, KK Altobelli, MJ Pencina… - Circulation, 2016 - Am Heart Assoc
Background—Current guidelines recommend statins in the primary prevention of
cardiovascular disease on the basis of predicted cardiovascular risk without directly …

Comparison of five major guidelines for statin use in primary prevention in a contemporary general population

MB Mortensen, BG Nordestgaard - Annals of internal medicine, 2018 - acpjournals.org
Background: Five major organizations recently published guidelines for using statins to
prevent atherosclerotic cardiovascular disease (ASCVD): in 2013, the American College of …

Continuation of statin treatment and all-cause mortality: a population-based cohort study

V Shalev, G Chodick, H Silber, E Kokia… - Archives of internal …, 2009 - jamanetwork.com
Background The beneficial effects of statins on cardiovascular mortality in secondary
prevention have been established in several long-term, placebo-controlled trials. However …