A bird's eye view of NK cell receptor interactions with their MHC class I ligands

PM Saunders, JP Vivian, GM O'Connor… - Immunological …, 2015 - Wiley Online Library
The surveillance of target cells by natural killer (NK) cells utilizes an ensemble of inhibitory
and activating receptors, many of which interact with major histocompatibility complex …

NK cells: tuned by peptide?

J Das, SI Khakoo - Immunological reviews, 2015 - Wiley Online Library
Natural killer cells express multiple receptors for major histocompatibility complex (MHC)
class I, including the killer cell immunoglobulin‐like receptors (KIR s) and the C‐type lectin …

NK-cell receptors and recognition of MHC class I molecules

M López-Botet, L Moretta, J Strominger - Immunology today, 1996 - cell.com
[I n recent years, it has become clear that specific recognition of major histocompatibility
complex (MHC) class I molecules on target cells may repress natural killer (NKJ-cell …

Interaction between the human NK receptors and their ligands

M Vales-Gomez, H Reyburn… - Critical Reviews™ in …, 2000 - dl.begellhouse.com
ABSTRACT NK cells are physiologically important in a number of contexts: mediating
immunity against viruses, intracellular bacteria and parasites, and in anti-tumour immune …

HLA class I recognition by killer cell Ig-like receptors

EO Long, S Rajagopalan - Seminars in immunology, 2000 - Elsevier
Copyright 2000 Academic PressNatural killer (NK) cell activation is regulated by a
combination of positive and negative signals coming from repertoires of activating and …

Recognition events that inhibit and activate natural killer cells

DH Raulet - Current opinion in immunology, 1996 - Elsevier
Natural killer (NK) cells exhibit specificity for MHC class I molecules in their interactions with
target cells. Instead of activating the cells, the recognition of class I molecules on target cells …

Structural basis of MHC class I recognition by natural killer cell receptors

MW Sawicki, N Dimasi, K Natarajan… - Immunological …, 2001 - Wiley Online Library
Natural killer (NK)‐cell function is regulated by NK receptors that recognize MHC class I
(MHC‐I) molecules on target cells. Two structurally distinct families of NK receptors have …

Molecular analyses of the interactions between human NK receptors and their HLA ligands

M Valés-Gómez, H Reyburn, J Strominger - Human immunology, 2000 - Elsevier
NK cell cytotoxicity is regulated by the action of multiple families of receptors. The
interactions of these receptors with their ligands control different activating/inhibiting signal …

Hierarchy of the human natural killer cell response is determined by class and quantity of inhibitory receptors for self-HLA-B and HLA-C ligands

J Yu, G Heller, J Chewning, S Kim… - The Journal of …, 2007 - journals.aai.org
The interaction of NK inhibitory killer Ig-like receptors (KIRs) with self-MHC class I molecules
mediates NK tolerance to self while conferring functional competence. Through single-cell …

Paired inhibitory and triggering NK cell receptors for HLA class I molecules

M López-Botet, T Bellón, M Llano, F Navarro… - Human immunology, 2000 - Elsevier
Human natural killer (NK) cells specifically interact with major histocompatibility complex
(MHC) class I molecules employing different receptor systems, shared with subsets of αβ …