Garcinol exhibits anti-neoplastic effects by targeting diverse oncogenic factors in tumor cells

V Aggarwal, HS Tuli, J Kaur, D Aggarwal, G Parashar… - Biomedicines, 2020 - mdpi.com
Garcinol, a polyisoprenylated benzophenone, is the medicinal component obtained from
fruits and leaves of Garcinia indica (G. indica) and has traditionally been extensively used …

Garcinol and its role in chronic diseases

AK Behera, MM Swamy, N Natesh… - … Nutraceuticals and Chronic …, 2016 - Springer
The various bioactive compounds isolated from leaves and fruits of Garcinia sps plants,
have been characterized and experimentally demonstrated to be anti-oxidant, anti …

Potential role of garcinol as an anticancer agent

N Saadat, SV Gupta - Journal of oncology, 2012 - Wiley Online Library
Garcinol, a polyisoprenylated benzophenone, is extracted from the rind of the fruit of
Garcinia indica, a plant found extensively in tropical regions. Although the fruit has been …

Garcinol inhibits tumour cell proliferation, angiogenesis, cell cycle progression and induces apoptosis via NF-κB inhibition in oral cancer

S Aggarwal, SN Das - Tumor Biology, 2016 - Springer
Garcinol, a polyisoprenylated benzophenone is extracted from the rind of the fruit of Garcinia
indica, a plant found extensively in tropical regions. Its ability to inhibit tumour growth has …

Garcinol inhibits cell proliferation and promotes apoptosis in pancreatic adenocarcinoma cells

MA Parasramka, SV Gupta - Nutrition and cancer, 2011 - Taylor & Francis
Garcinol, or polyisoprenylated benzophenone, isolated from the rind of fruiting bodies of
Garcinia indica, has been used in traditional medicine for its potential antiinflammatory and …

Garcinol: Current status of its anti-oxidative, anti-inflammatory and anti-cancer effects

C Liu, PCL Ho, FC Wong, G Sethi, LZ Wang, BC Goh - Cancer letters, 2015 - Elsevier
Garcinol is the main medicinal component of the dried fruit rind of Garcinia indica (G. indica),
which has traditionally been extensively used to treat gastric ailments and skin irritation. In …

Anticancer action of garcinol in vitro and in vivo is in part mediated through inhibition of STAT-3 signaling

A Ahmad, SH Sarkar, A Aboukameel, S Ali… - …, 2012 - academic.oup.com
Garcinol, obtained from Garcinia indica, has exhibited some promising anticancer activity. In
particular, our earlier work has demonstrated its ability to inhibit cell proliferation and …

Garcinol—a natural histone acetyltransferase inhibitor and new anti-cancer epigenetic drug

P Kopytko, K Piotrowska, J Janisiak… - International Journal of …, 2021 - mdpi.com
Garcinol extracted from Garcinia indica fruit peel and leaves is a polyisoprenylated
benzophenone. In traditional medicine it was used for its antioxidant and anti-inflammatory …

Garcinol exhibits anti-proliferative activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells

T Ranjbarnejad, M Saidijam… - Human & …, 2017 - journals.sagepub.com
Background: Colorectal cancer is the fourth leading cause of death. Various natural
compounds are known to have antitumor properties. Garcinol, a polyisoprenylated …

Antitumor activity of garcinol in human prostate cancer cells and xenograft mice

Y Wang, ML Tsai, LY Chiou, CT Ho… - Journal of agricultural …, 2015 - ACS Publications
Garcinol, which is isolated from fruit rinds of Garcinia indica, is a polyisoprenylated
benzophenone. It has been studied for its antitumor activity by inducing apoptosis and …