Transcription factor IID (TFIID) activity can be regulated by cellular signals to specifically
alter transcription of particular subsets of genes. Alternative splicing of TFIID subunits is …

Development is a highly controlled process of cell proliferation and differentiation driven by
mechanisms of dynamic gene regulation. Specific DNA binding factors for establishing cell …

The diverse transcriptional mechanisms governing cellular differentiation and development
of mammalian tissue remains poorly understood. Here we report that TAF7L, a paralogue of …

The understanding of the mechanisms that regulate gene expression to establish
differentiation programs and determine cell lineages, is one of the major challenges in …

TAF 4b is a cell type‐specific subunit of the general transcription factor TFIID. Here, we show
that TAF 4b is highly expressed in embryonic stem cells (ESC) and is down‐regulated upon …

Expression of general transcription factor and co-activator TAF4 varies during development
and in the processes of cell differentiation with suggested connection to neurodegenerative …

The majority of the TATA-binding protein (TBP)-associated factors (TAFs) that constitute
transcription factor II D (TFIID) contain histone fold motifs (HFMs). Our previous results …

Abstract TAF4 (TATA-binding protein-associated factor 4) and its paralogue TAF4b are
components of the TFIID core module. We inactivated the murine Taf4a gene to address …

Despite tremendous advances in the diagnosis and treatment of NSCLC, the morbidity and
mortality of NSCLC still rank high worldwide. Epithelial-mesenchymal transition (EMT) is …

The human general transcription factor TFIID is composed of the TATA-binding protein (TBP)
and 13 TBP-associated factors (TAFs). In eukaryotic cells, TFIID is thought to nucleate RNA …