Overexpression of microRNA-155 enhances the efficacy of dendritic cell vaccine against breast cancer
ABSTRACT MicroRNA 155 (miR-155) plays important roles in the regulation of the
development and functions of a variety of immune cells. We previously revealed a vital role …
development and functions of a variety of immune cells. We previously revealed a vital role …
microRNA-155 deficiency impairs dendritic cell function in breast cancer
J Wang, S Iwanowycz, F Yu, X Jia, S Leng… - …, 2016 - Taylor & Francis
In antitumor immunity, dendritic cells (DCs) capture, process, and present tumor antigens to
T cells, initiating a tumoricidal response. However, DCs are often dysfunctional due to their …
T cells, initiating a tumoricidal response. However, DCs are often dysfunctional due to their …
Breast cancer cell–derived microRNA-155 suppresses tumor progression via enhancing immune cell recruitment and antitumor function
J Wang, Q Wang, Y Guan, Y Sun… - The Journal of …, 2022 - Am Soc Clin Investig
Evidence suggests that increased microRNA-155 (miR-155) expression in immune cells
enhances antitumor immune responses. However, given the reported association of miR …
enhances antitumor immune responses. However, given the reported association of miR …
MicroRNA-155 expression is enhanced by T-cell receptor stimulation strength and correlates with improved tumor control in melanoma
A Martinez-Usatorre, LF Sempere, SJ Carmona… - Cancer immunology …, 2019 - AACR
Abstract microRNAs are short noncoding RNAs that regulate protein expression
posttranscriptionally. We previously showed that miR-155 promotes effector CD8+ T-cell …
posttranscriptionally. We previously showed that miR-155 promotes effector CD8+ T-cell …
In vivo microRNA-155 expression influences antigen-specific T cell-mediated immune responses generated by DNA vaccination
CP Mao, L He, YC Tsai, S Peng, TH Kang, X Pang… - Cell & bioscience, 2011 - Springer
Background MicroRNA (miRNA) molecules are potent mediators of post-transcriptional gene
silencing that are emerging to be critical in the regulation of innate and adaptive immunity …
silencing that are emerging to be critical in the regulation of innate and adaptive immunity …
[HTML][HTML] Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity
TB Huffaker, R Hu, MC Runtsch, E Bake, X Chen… - Cell reports, 2012 - cell.com
An increased understanding of antitumor immunity is necessary for improving cell-based
immunotherapies against human cancers. Here, we investigated the roles of two immune …
immunotherapies against human cancers. Here, we investigated the roles of two immune …
The role of miR-155 in antitumor immunity
K Kalkusova, P Taborska, D Stakheev, D Smrz - Cancers, 2022 - mdpi.com
Simple Summary MiR-155 appears to be a significant regulator of immune responses
against tumors. The aim of this review is to provide an overview of miR-155 function in …
against tumors. The aim of this review is to provide an overview of miR-155 function in …
A role for miR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice
A productive immune response requires transient upregulation of the microRNA miR-155 in
hematopoietic cells mediating innate and adaptive immunity. In order to investigate miR-155 …
hematopoietic cells mediating innate and adaptive immunity. In order to investigate miR-155 …
[HTML][HTML] MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer
JC Dudda, B Salaun, Y Ji, DC Palmer, GC Monnot… - Immunity, 2013 - cell.com
MicroRNAs (miRNAs) regulate the function of several immune cells, but their role in
promoting CD8+ T cell immunity remains unknown. Here we report that miRNA-155 is …
promoting CD8+ T cell immunity remains unknown. Here we report that miRNA-155 is …
MicroRNA-125b potentiates macrophage activation
AA Chaudhuri, AYL So, N Sinha… - The Journal of …, 2011 - journals.aai.org
Abstract MicroRNA (miR)-125b expression is modulated in macrophages in response to
stimulatory cues. In this study, we report a functional role of miR-125b in macrophages. We …
stimulatory cues. In this study, we report a functional role of miR-125b in macrophages. We …