Background and aim Osteoarthritis (OA) is a multiple factorial disease with unidentified
specific markers. The alternate method such as biochemical and genetic markers for the …

Abstract Background Interleukin-6 (IL-6) gene regulates IL-6 levels, interplay of which has
been found to influence pathophysiology of osteoarthritis (OA). Polymorphism within …

Osteoarthritis (OA) is one of the most common musculoskeletal diseases of adults
worldwide. Inflammation plays a crucial part in OA pathology, but role of cytokines is still …

Osteoarthritis is the most common of the arthropathies. Previous population-based
epidemiologic studies have estimated the prevalence of osteoarthritis by age, gender, race …

Osteoarthritis (OA), the most common form of arthritis, is a highly debilitating disease of the
joints and can lead to severe pain and disability. There is no cure for OA. Current treatments …

Objective We aimed to compare the genetic contribution to osteoarthritis (OA) versus other
rheumatic/musculoskeletal diseases (RMDs) in the same population and to explore the role …

Idiopathic or primary osteoarthritis is a progressive musculoskeletal disease of diarthrodial
synovial joints, whereas secondary osteoarthritis generally arises from an antecedent …

Although the multifactorial nature of osteoarthritis (OA) is well recognized, genetic factors
have been found to be strong determinants of the disease. Evidence of a genetic influence …

Personal, non-commercial use only. The Journal of Rheumatology. Copyright© 2004. All
rights reserved. prevalence of OA in their siblings (who have a genetic exposure) with that in …

Osteoarthritis (OA) is becoming a significant problem worldwide. Pain and loss of joint
function have a major impact on an individual's quality of life and through loss of time at work …