Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variant

W Zhang, K Shi, Q Geng, G Ye… - Proceedings of the …, 2022 - National Acad Sciences
The sudden emergence and rapid spread of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) omicron variant has raised questions about its animal …

Structural evolution of SARS-CoV-2 omicron in human receptor recognition

W Zhang, K Shi, Q Geng, M Herbst, M Wang… - Journal of …, 2023 - Am Soc Microbiol
Understanding the evolutionary strategies of the SARS-CoV-2 omicron variant is crucial for
comprehending the COVID-19 pandemic and preventing future coronavirus pandemics. In …

Structural basis for human receptor recognition by SARS-CoV-2 Omicron variant BA. 1

Q Geng, K Shi, G Ye, W Zhang, H Aihara, F Li - Journal of Virology, 2022 - Am Soc Microbiol
The highly contagious and fast-spreading omicron variant of SARS-CoV-2 infects the
respiratory tracts efficiently. The receptor-binding domain (RBD) of the omicron spike protein …

Spike protein-independent attenuation of SARS-CoV-2 Omicron variant in laboratory mice

S Liu, P Selvaraj, K Sangare, B Luan, TT Wang - Cell Reports, 2022 - cell.com
Despite being more transmissible, the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) Omicron variant only causes milder diseases in laboratory animals, often …

SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2

L Wu, L Zhou, M Mo, T Liu, C Wu, C Gong… - Signal transduction and …, 2022 - nature.com
SARS-coronavirus-2 (SARS-CoV-2) Omicron variant (B. 1.1. 529) is of great concern to the
world due to its multiple mutations that may have an impact on transmissibility and immune …

SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein–ACE2 complex

D Mannar, JW Saville, X Zhu, SS Srivastava… - Science, 2022 - science.org
The newly reported Omicron variant is poised to replace Delta as the most prevalent severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant across the world. Cryo …

[HTML][HTML] Origin and evolutionary analysis of the SARS-CoV-2 Omicron variant

Y Sun, W Lin, W Dong, J Xu - Journal of biosafety and biosecurity, 2022 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved rapidly
into new variants throughout the pandemic. The Omicron variant has more than 50 …

Binding of human ACE2 and RBD of omicron enhanced by unique interaction patterns among SARS‐CoV‐2 variants of concern

S Kim, Y Liu, M Ziarnik, S Seo, Y Cao… - Journal of …, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus causing COVID‐
19, has continued to mutate and spread worldwide despite global vaccination efforts. In …

Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s

L Li, P Han, B Huang, Y Xie, W Li, D Zhang, P Han… - Cell Discovery, 2022 - nature.com
The Omicron variant of SARS-CoV-2 carries multiple unusual mutations, particularly in the
receptor-binding domain (RBD) of the spike (S) protein. Moreover, host-adapting mutations …

Different pathogenesis of SARS-CoV-2 Omicron variant in wild-type laboratory mice and hamsters

YN Zhang, ZR Zhang, HQ Zhang, N Li… - … and Targeted Therapy, 2022 - nature.com
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) continues to disrupt global public health since its first report in December …