We assessed the geographical distribution of C9orf72 G 4 C 2 expansions in a pan‐E
uropean frontotemporal lobar degeneration (FTLD) cohort (n= 1,205), ascertained by the E …

Objective To characterize patients with frontotemporal lobar degeneration (FTLD) with a
repeat expansion mutation in the gene C9orf72, and to determine whether there are …

Objective: To determine the frequency of a hexanucleotide repeat expansion in C9ORF72, a
gene of unknown function implicated in frontotemporal dementia (FTD) and amyotrophic …

The discovery of the C9ORF72 hexanucleotide repeat expansion in 2011 and the immediate
realisation of a remarkably high prevalence in both familial and sporadic frontotemporal …

Since the discovery of the C9orf72 repeat expansion as the most common genetic cause of
frontotemporal dementia (FTD) and amyotrophic lateral sclerosis, it has increasingly been …

Objective: Expansions of more than 30 hexanucleotide repetitions in the C9ORF72 gene are
a common cause of frontotemporal dementia (FTD) or amyotrophic lateral sclerosis (ALS) …

Background We aimed to accurately estimate the frequency of a hexanucleotide repeat
expansion in C9orf72 that has been associated with a large proportion of cases of …

Background Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration
(FTLD) are extremes of a clinically, pathologically, and genetically overlapping disease …

Abstract The GGGGCC (G 4 C 2) repeat expansion in C9ORF72 is the most common cause
of familial amyotrophic lateral sclerosis (ALS), frontotemporal lobar dementia (FTLD) and …

C9orf72 repeat expansions is a major cause of familial frontotemporal dementia (FTD) and
amyotrophic lateral sclerosis (ALS) worldwide. Sizes of< 20 hexanucleotide repeats are …