Interindividual variation in mean leukocyte telomere length (LTL) is associated with cancer
and several age-associated diseases. We report here a genome-wide meta-analysis of …

Telomeres, the end fragments of chromosomes, play key roles in cellular proliferation and
senescence. Here we characterize the genetic architecture of naturally occurring variation in …

Leukocyte telomere length (LTL) is a heritable biomarker of genomic aging. In this study, we
perform a genome-wide meta-analysis of LTL by pooling densely genotyped and imputed …

Genetic factors underlying leukocyte telomere length (LTL) may provide insights into
telomere homeostasis, with direct links to disease susceptibility. Genetic evaluation of …

Inherited genetic variation influencing leukocyte telomere length provides a natural
experiment for testing associations with health outcomes, more robust to confounding and …

Telomere length is a crucial factor for both normal chromosomal function and senescence.
Mean telomere length in humans shows considerable interindividual variation and strong …

Telomeres play a central role in cellular senescence and cancer pathobiology and are
associated with age-related diseases such as atherosclerosis and dementia. Telomere …

Remarkable progress has been made during the last 2 decades in understanding telomere
biology at the molecular and cellular levels. Clinical epidemiology research of human …

Mean telomere length (TL) in blood cells is heritable and has been reported to be
associated with risks of several diseases, including cancer. We conducted a meta-analysis …

In a broad range of species—including humans—it has been demonstrated that telomere
length declines throughout life and that it may be involved in cell and organismal …