The study of the extreme limits of human lifespan may allow a better understanding of how
human beings can escape, delay, or survive the most frequent age-related causes of …

An aging global population poses substantial challenges to society [1]. Centenarians are a
model for healthy aging because they have reached the extreme limit of life by escaping …

The changing physiology and lifestyle of elderly people affect the gut microbiota
composition, the changes of which can, in turn, affect the health maintenance of the ageing …

The gut microbiome of long-lived people display an increasing abundance of subdominant
species, as well as a rearrangement in health-associated bacteria, but less is known about …

The gut microbiota (GM) is a complex, evolutionarily molded ecological system, which
contributes to a variety of physiological functions. The GM is highly dynamic, being sensitive …

The gut microbiota shows a wide inter-individual variation, but its within-individual variation
is relatively stable over time. A functional core microbiome, provided by abundant bacterial …

The human gastrointestinal (GI) tract harbors the largest number and concentration of
microbes found in the human body. Perturbations in the gut microbial ecosystem have also …

Gut microbiota (GM) is a dynamic organ throughout the lifespan. Aging is a complex process
that comprises a plethora of mechanisms such as senescence, immunosenescence and …

Our gut microbiota is a complex and dynamic ecosystem with a paramount role in shaping
our metabolic and immunological functions. Recent research suggests that aging may …

Background Age-related physiological changes in the gastrointestinal tract, as well as
modifications in lifestyle, nutritional behaviour, and functionality of the host immune system …