T. brucei brucei released a lymphocyte triggering factor (TLTF), which triggered purified
CD8+, but not CD4+, T cells to interferon y (IFN-T) mRNA expression and secretion and to …

The hemoflagellate Trypanosoma brucei (T. b.) is the cause of African sleeping sickness. T.
b. brucei which is pathogenic for rodents but nonpathogenic for humans was used to …

An early and essential event in the protective immune response against most viruses and
protozoa is the production of interferon-γ (IFN-γ). In contrast, during infection with African …

African trypanosomes are pathogens for humans and livestock. They are single‐cell, extra‐
cellular parasites that cause persistent infections of the blood and induce profound …

Experimental infections of mice with the African trypanosome Trypanosoma brucei lead to a
profound state of T-cell unresponsiveness in the lymph node cell (LNC) compartment. This …

A protein factor that stimulates CD8+ lymphocytes to produce and secrete IFN‐γ has been
purified from Trypanosoma brucei brucei (Tb brucei). This was accomplished by raising …

T-cell proliferative responses of lymph node cells are profoundly suppressed during
experimental infections of mice with Trypanosoma brucei. The active suppression of lymph …

In order to evaluate during experimental Trypanosoma brucei infections the potential role of
tumor necrosis factor alpha (TNF-α) in the host-parasite interrelationship, C57BL/6 TNF-α …

Abstract Development of classically activated macrophages (M1 cells) is a prerequisite to
controlling parasite growth and therefore resistance to African trypanosomiasis. However, if …

Infections of highly susceptible BALB/c mice with virulent strains of Trypanosoma
congolense or Trypanosoma brucei result in rapid death (8 days). We have previously …