One of the major challenges in the development of targeted nanoparticles (NPs) for cancer
therapy is to discover targeting ligands that allow for differential binding and uptake by the …

Nucleic acid ligands (aptamers) are potentially well suited for the therapeutic targeting of
drug encapsulated controlled release polymer particles in a cell-or tissue-specific manner …

Targeted cancer therapy is currently the leading modality to enhance treatment selectivity
and efficacy, as well as to minimize untoward toxicity to healthy tissues. Herein, we devised …

Nanoparticles (NPs) are commonly functionalized using targeting ligands to drive their
selective uptake in cells of interest. Typical target cell types are cancer cells, which often …

Over the past decades there have been exciting and rapid developments of highly specific
molecules to bind cancer antigens that are overexpressed on the surfaces of malignant …

Lung cancer is the leading cause of cancer mortality worldwide, resulting in 88% deaths of
all diagnosed patients. Hence, novel therapeutic modalities are urgently needed. Single …

Computed tomography (CT) is one of the most useful diagnostic tools among commonly
used biomedical imaging techniques, which also include magnetic resonance imaging …

One hundred years ago, Dr. Paul Ehrlich popularized the" magic bullet" concept for cancer
therapy in which an ideal therapeutic agent would only kill the specific tumor cells it targeted …

Local delivery of anticancer agents has the potential to maximize treatment efficacy and
minimize the acute and long-term systemic toxicities. Here, we used unsupervised …

Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …