Crispr-cas based biosensing: A fast-expanding molecular diagnostic tool

S Singh, R Thakran, A Kaushal, RV Saini, A Saini… - Microchemical …, 2024 - Elsevier
Clustered regularly interspaced short palindromic sequences (CRISPR)-Cas is one of the
most promising gene editing systems. Defined by its specificity, sensitivity, and high base …

Signal amplification and output of CRISPR/Cas-based biosensing systems: A review

SY Wang, YC Du, DX Wang, JY Ma, AN Tang… - Analytica Chimica …, 2021 - Elsevier
CRISPR (clustered regularly interspaced short palindromic repeats)/Cas (CRISPR-
associated) proteins are powerful gene-editing tools because of their ability to accurately …

CRISPR/Cas-engineered technology: Innovative approach for biosensor development

TS Zavvar, Z Khoshbin, M Ramezani… - Biosensors and …, 2022 - Elsevier
On-site and real-time clinical monitoring have been progressed dramatically by integrating
biosensor science with portable digital electronic technology. Clustered regularly …

[HTML][HTML] Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas Advancement in Molecular Diagnostics and Signal Readout Approaches

MZ Ahmed, P Badani, R Reddy, G Mishra - The Journal of Molecular …, 2021 - Elsevier
Discovery of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas
system has greatly improved the gene editing technology. Their applications in the area of …

Application of CRISPR/Cas Technology in Biological Nano‐Analysis

P Liu, G Aodeng, L Ga, J Ai - ChemistrySelect, 2023 - Wiley Online Library
Currently, with the growing global demand for infectious disease diagnostics, environmental
testing and food safety, CRISPR‐Cas (Clustered Regularly Interspaced Short Palindromic …

CRISPR/Cas systems for the detection of nucleic acid and non-nucleic acid targets

W Su, J Li, C Ji, C Chen, Y Wang, H Dai, F Li, P Liu - Nano Research, 2023 - Springer
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
(Cas) systems are becoming powerful tools for disease biomarkers detection. Due to the …

[HTML][HTML] CRISPR-Cas assisted diagnostics: A broad application biosensing approach

A Masi, A Antonacci, M Moccia, V Frisulli… - TrAC Trends in …, 2023 - Elsevier
In addition to its remarkable genome editing capability, the CRISPR-Cas system has proven
to be very effective in many fields of application, including the biosensing of pathogenic …

Research progress of CRISPR-based biosensors and bioassays for molecular diagnosis

K Chen, Z Shen, G Wang, W Gu, S Zhao… - … in Bioengineering and …, 2022 - frontiersin.org
CRISPR/Cas technology originated from the immune mechanism of archaea and bacteria
and was awarded the Nobel Prize in Chemistry in 2020 for its success in gene editing …

CRISPR/Cas-powered nanobiosensors for diagnostics

QA Phan, LB Truong, D Medina-Cruz, C Dincer… - Biosensors and …, 2022 - Elsevier
CRISPR diagnostics (CRISPR-Dx) offer a wide range of enhancements compared to
traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the …

Advancements in CRISPR-based biosensing for next-gen point of care diagnostic application

A Kumaran, N Jude Serpes, T Gupta, A James… - Biosensors, 2023 - mdpi.com
With the move of molecular tests from diagnostic labs to on-site testing becoming more
common, there is a sudden rise in demand for nucleic acid-based diagnostic tools that are …