Preferential loss of basal ganglia neurons and terminals occurs in Huntington's disease
(HD). Terminals of preproen‐kephalin medium‐size spiny neurons are more vulnerable than …

Differential loss of neurons and terminals occurs in Huntington's disease. Neurons
expressing preproenkephalin (PPE) appear to be more vulnerable than neurons expressing …

Previous studies have revealed a loss of enkephalin immunoreactivity in the terminals of
striatal neurons projecting to the external globus pallidus in patients with early grades of …

In early adult-onset Huntington's disease (HD), enkephalinergic striatopallidal projection
neurons show preferential loss, reduced preproenkephalin (PPE) expression in surviving …

Huntington disease (HD) is characterized by the loss of striatal projection neurons, which
constitute the vast majority of striatal neurons. To determine whether there is differential loss …

The expression of enkephalin and substance P messenger RNAs was examined in the
caudate-putamen of human post mortem tissue from control and Huntington's disease tissue …

Huntington's disease is a devastating progressive neurodegenerative illness characterized
by massive neuronal loss in the striatum. It is caused by the presence of an expanded CAG …

Previous studies have shown that in advanced cases of Huntington's disease, enkephalin-
immunoreactive striatal projections to the external globus pallidus may be more affected …

Prior studies suggest differences exist among striatal projection neuron types in their
vulnerability to Huntington's disease (HD). In the present study, we immunolabeled the fibers …

We examined the distribution of neuropeptide Y immunoreactive local circuit neurons and
nonphosphorylated neurofilament (SMI 32) immunoreactive pyramidal projection neurons in …