Background Antibiotic therapy has been proposed as an alternative to surgery for the
treatment of appendicitis. Methods We conducted a pragmatic, nonblinded, noninferiority …

Antibiotics vs. Appendectomy for Appendicitis In this randomized trial comparing antibiotic
treatment with appendectomy in patients with appendicitis, the percentage of patients in the …

Background This aim of this study was to provide an updated meta-analysis comparing
antibiotic therapy with appendicectomy in adults (16 years or older) with uncomplicated …

Objective: The aim was to investigate available evidence regarding effectiveness and safety
of surgical versus conservative treatment of acute appendicitis. Summary of Background …

Importance An increasing amount of evidence supports the use of antibiotics instead of
surgery for treating patients with uncomplicated acute appendicitis. Objective To compare …

Background Antibiotic treatment has been shown to be effective in treating selected patients
with acute appendicitis, and three randomized controlled trials (RCTs) have compared the …

Background: The objective was to conduct a meta-analysis of randomized controlled trials
evaluating the efficacy and morbidity of the management of acute uncomplicated (no …

Background Uncomplicated acute appendicitis has been managed traditionally by early
appendicectomy. However, recently, there has been increasing interest in the potential for …

Background The efficacy of antibiotics in appendicitis remains controversial, and physicians
are not confident in prescribing antibiotics as the first line treatment. This network meta …

Importance Short-term results support antibiotics as an alternative to surgery for treating
uncomplicated acute appendicitis, but long-term outcomes are not known. Objective To …