Dolutegravir-based regimen for maintenance of viral suppression in people living with HIV: 48-week results in real-life setting

D Di Carlo, F Falasca, E Palermo… - AIDS Research and …, 2021 - liebertpub.com
To evaluate the efficacy, safety, and tolerability of switching to a dolutegravir (DTG)-based
regimen in a cohort of virological suppressed HIV-infected patients who have previously …

[HTML][HTML] Effectiveness and Tolerability of Dual Therapy with Dolutegravir Plus Darunavir/cobicistat in Treatment-Experienced Patients with HIV: A 144-Week Follow-Up

SW Kim, HW Jang, HH Chang, Y Kim… - Infection & …, 2024 - ncbi.nlm.nih.gov
Background A dual regimen with dolutegravir plus cobicistat-boosted darunavir (DTG+
DRV/c) is a promising alternative for patients with human immunodeficiency virus (HIV) with …

[PDF][PDF] Efficacy, safety and tolerability of dolutegravir-based combination antiretroviral therapy in clinical practice in HIV-infected patients: Results from a multicenter …

A De Vito, G Caruana, F Clark, G Nunnari… - Infect. Dis. Trop …, 2019 - infectiousjournal.com
Objective: Dolutegravir (DTG) is a second-generation integrase inhibitor (INI) characterized
by unboosted daily dosing, limited cross resistance, and a high barrier to resistance. We …

Dolutegravir monotherapy versus dolutegravir/abacavir/lamivudine for virologically suppressed people living with chronic human immunodeficiency virus infection: the …

L Hocqueloux, F Raffi, T Prazuck… - Clinical Infectious …, 2019 - academic.oup.com
Background We investigated whether dolutegravir (DTG) monotherapy could be used to
maintain virological suppression in people living with human immunodeficiency virus (HIV) …

Comparative safety and changes in immunologic and virologic parameters of dolutegravir versus efavirenz-based antiretroviral therapies among HIV Patients: A …

MA Ayal, AB Berha - HIV/AIDS-Research and Palliative Care, 2023 - Taylor & Francis
Background In combination with other two antiretroviral drugs, an efavirenz (EFV) or
dolutegravir (DTG)-based regimen is the treatment of choice for human immunodeficiency …

Effectiveness of dolutegravir-based antiretroviral therapy in a real-world setting in a Belgian cohort of 4101 HIV patients

R Nasreddine, E Florence, B Vandercam, M Moutschen… - AIDS, 2020 - journals.lww.com
Objective: To describe the treatment outcomes of patients receiving dolutegravir (DTG) in a
'real-world setting'in Belgium. Design: Retrospective, observational, multicenter cohort …

Efficacy and safety of two-drug regimens with dolutegravir plus rilpivirine or lamivudine in HIV-1 virologically suppressed people living with HIV

C Dueñas-Gutiérrez, L Buzón, R Pedrero-Tomé… - Viruses, 2023 - mdpi.com
Background: The high effectiveness and safety of the two-drug (2DRs) strategy using
dolutegravir (DTG) plus lamivudine (3TC) have led to international guidelines …

Effectiveness of once/day dolutegravir plus boosted darunavir as a switch strategy in heavily treated patients with human immunodeficiency virus

J Navarro, JR Santos, A Silva, J Burgos… - … : The Journal of …, 2019 - Wiley Online Library
Study Objective Dual therapy with once/day dolutegravir (DTG) plus boosted darunavir
(DRV/b) may be a suitable and effective strategy with a high genetic barrier to resistance in …

Predictors of virological failure in HIV‐1‐infected patients switching to dolutegravir maintenance monotherapy

IEA Wijting, SL Rutsaert, C Rokx, DM Burger… - HIV …, 2019 - Wiley Online Library
Objectives The Dolutegravir Monotherapy for HIV (DOMONO; NCT 02401828) study showed
that maintenance monotherapy with dolutegravir (DTG) is associated with virological failure …

Effectiveness and safety of dolutegravir two‐drug regimens in virologically suppressed people living with HIV: a systematic literature review and meta‐analysis of real …

YS Punekar, D Parks, M Joshi, S Kaur, L Evitt… - HIV …, 2021 - Wiley Online Library
Objectives Dolutegravir (DTG) is widely recommended within three‐drug regimens.
However, similar efficacy and tolerability have also been achieved with DTG within two‐drug …