Abstract Mycobacterium tuberculosis (MTB) infects 30% of all humans and kills someone
every 20–30 s. Here we report genome-wide binding for~ 80% of all predicted MTB …

The resilience of Mycobacterium tuberculosis (MTB) is largely due to its ability to effectively
counteract and even take advantage of the hostile environments of a host. In order to …

Background Mycobacterium tuberculosis senses and responds to the shifting and hostile
landscape of the host. To characterize the underlying intertwined gene regulatory network …

Mycobacterium tuberculosis (MTB) is a pathogenic bacterium responsible for 12 million
active cases of tuberculosis (TB) worldwide. The complexity and critical regulatory …

The prediction of operons in Mycobacterium tuberculosis (MTB) is a first step toward
understanding the regulatory network of this pathogen. Here we apply a statistical model …

The Mycobacterium tuberculosis complex (MTBC) members display different host-
specificities and virulence phenotypes. Here, we have performed a comprehensive RNAseq …

Regulating responses to stress is critical for all bacteria, whether they are environmental,
commensal, or pathogenic species. For pathogenic bacteria, successful colonization and …

The sudden increase in information derived from the completed Mycobacterium tuberculosis
(Mtb) genome sequences has revealed the need for approaches capable of converting raw …

Macrophages are central to host defense against microbes, but intracellular pathogens have
evolved to evade their antimicrobial functions. Mycobacterium tuberculosis (MTB) has …

Although tuberculosis remains a substantial global threat, the mechanisms that enable
mycobacterial persistence and replication within the human host are ill defined. This study …