The thrombin generation test (TGT) has demonstrated utility in evaluating overall hemostatic
capacity both in bleeding and thrombotic disorders. Although the test is currently well …

We have previously shown that standardisation and normalization of results improve the
intercentre variability of the calibrated automated thrombin generation test (TGT). We …

Background Thrombin generation (TG) is a better determinant of the overall function of the
hemostatic system than the routinely used clotting time‐based assays. Nowadays, TG is …

Thrombin is the central enzyme in the coagulation cascade. Estimation of an individual's
potential to generate thrombin may correlate more closely with a hyper‐or hypo‐coagulable …

Background Thrombin generation (TG) assays evaluate the balance between pro‐and
anticoagulant forces, to better assess bleeding and thrombotic risks. Although TG readouts …

Determining patient's coagulation profile, ie detecting a bleeding tendency or the opposite, a
thrombotic risk, is crucial for clinicians in many situations. Routine coagulation assays and …

Thrombin is the pivotal enzyme in the biochemistry of secondary hemostasis crucial to
maintaining homeostasis of hemostasis. In contrast to routine coagulation tests (PT or aPTT) …

Readouts from the thrombin generation (TG) assay (TGA) have been used to predict the
effects of hemostatic drugs in hemophilic patients [1]. There is better correlation between an …

BACKGROUND The calibrated automated thrombogram (CAT) assay in plasma is a
versatile tool to investigate patients with hypo-or hypercoagulable phenotypes. The …

Dear Sir, Thrombin is one of the central enzymes in blood coagulation and both the rate of
thrombin formation and the total amount of thrombin formed can be considered to be a …