According to the cancer progression model, several events are required for the progression
from normal epithelium to carcinoma. Due to their extended life span, stem cells would …

Cancer stem cells and their potential roles in tumor heterogeneity are currently subjects of
intense investigation. Studies suggest that these cells may develop from any normal cell and …

With evidence emerging in support of a cancer stem-cell model of carcinogenesis, it is of
paramount importance to identify and image these elusive cells in their natural environment …

Table 2: Strategies and Therapies Targeting Cancer Stem Cells significant proportion of
patients continue to experience recurrence after adjuvant treatment, and survival associated …

Stem cells and cancer are inextricably linked; the process of carcinogenesis initially affects
normal stem cells or their closely related progenitors and then, at some point, neoplastic …

Emerging evidence has shown that the capacity of a tumor to grow and propagate is
dependent on a small subset of cells, termed “cancer stem cells.” Confirmation of the …

The theory of cancer stem cells states that a subset of cancer cells within a tumor has the
ability to self-renew and differentiate. Only those cells within a tumor that have these two …

Although the concept that cancers arise from “stem cells” or “germ cells” was first proposed
about 150 years ago, it is only recently that advances in stem cell biology have given new …

Cancer stem cells have been identified in a variety of tumors. Characterization of these cells,
determining how they originate and developing relevant assays is a work in progress …

The relationships between cancer and stemness have a long history that is traced here.
From the mid‐19th century when the first theory on the embryonic origin of cancer was …