Genetic susceptibility to chronic kidney disease–some more pieces for the heritability puzzle: Genetic predisposition to kidney disease

M Cañadas-Garre, K Anderson, R Cappa… - Frontiers in …, 2019 - pure.qub.ac.uk
Chronic kidney disease (CKD) is a major global health problem with an increasing
prevalence partly driven by aging population structure. Both genomic and environmental …

[HTML][HTML] Genetic susceptibility to chronic kidney disease–some more pieces for the heritability puzzle

M Cañadas-Garre, K Anderson, R Cappa… - Frontiers in …, 2019 - frontiersin.org
Chronic kidney disease (CKD) is a major global health problem with an increasing
prevalence partly driven by aging population structure. Both genomic and environmental …

Chronic kidney disease: novel insights from genome-wide association studies

CA Böger, IM Heid - Kidney and Blood Pressure Research, 2011 - karger.com
Chronic kidney disease (CKD) is common, affecting about 10% of the general population,
and causing significant morbidity and mortality. Apart from the risk conferred by traditional …

Multiple loci associated with indices of renal function and chronic kidney disease

A Köttgen, NL Glazer, A Dehghan, SJ Hwang, R Katz… - Nature …, 2009 - nature.com
Chronic kidney disease (CKD) has a heritable component and is an important global public
health problem because of its high prevalence and morbidity. We conducted genome-wide …

Genetic investigations of kidney disease: Core curriculum 2013

Y Li, A Köttgen - American journal of kidney diseases, 2013 - ajkd.org
It has long been known that inherited kidney disor-ders such as polycystic kidney disease
(PKD) can be caused by mutations in a single gene. These disorders are termed monogenic …

Genetic epidemiology of chronic kidney disease

MM Estrella, CJ Sperati, WHL Kao… - Current opinion in …, 2010 - journals.lww.com
Genetic epidemiology of chronic kidney disease : Current Opinion in Nephrology and
Hypertension Genetic epidemiology of chronic kidney disease : Current Opinion in …

A clustering approach to improve our understanding of the genetic and phenotypic complexity of chronic kidney disease

A Eoli, S Ibing, C Schurmann, GN Nadkarni… - Scientific Reports, 2024 - nature.com
Chronic kidney disease (CKD) is a complex disorder that causes a gradual loss of kidney
function, affecting approximately 9.1% of the world's population. Here, we use a soft …

[HTML][HTML] Genetics of Kidney Diseases

MH de Borst, HF Gu - Frontiers in Genetics, 2020 - frontiersin.org
Worldwide, more than 850 million people have chronic kidney disease (CKD)(Jager et al.,
2019). CKD can be caused by a variety of individual diseases including primary kidney …

Genetic and epigenetic factors influencing chronic kidney disease

LJ Smyth, S Duffy, AP Maxwell… - American Journal of …, 2014 - journals.physiology.org
Chronic kidney disease (CKD) has become a serious public health problem because of its
associated morbidity, premature mortality, and attendant healthcare costs. The rising …

Genetic studies in chronic kidney disease: interpretation and clinical applicability.

A Witasp, L Nordfors, JJ Carrero, K Luttropp… - Journal of …, 2012 - europepmc.org
The tools of modern molecular biology are evolving rapidly, resulting in vastly more efficient
approaches to illuminating human genetic variations and their effects on common …