Zinc is a crucial nutritional component required for the normal development and
maintenance of immune functions. It has been reported that zinc is a potent inhibitor of DNA …

High concentrations of zinc salts (500 m̈M and greater) are known to inhibit apoptosis in a
variety of systems. However, closer examination of dose effects revealed that lower …

There is a great deal of interest in chemicals and biochemicals that can modulate apoptosis.
As will be discussed, zinc, an essential trace element, can induce as well as block …

This review summarizes the evidence that apoptosis is modulated by intracellular excess or
deficiency of Zn2+, considers mechanisms whereby Zn2+ may influence apoptosis, and …

Alterations in intracellular Zn 2+ concentrations are believed to play a crucial role in
modulating apoptosis. The observation that Zn 2+ deficiency can induce cell death both in …

Apoptosis—or programmed cell death—is an active type of cell death, occurring in several
pathophysiological conditions. One of the most important characteristics of apoptosis is that …

Chelation of intracellular zinc triggers apoptosis in mature thymocytes. - Abstract - Europe
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Non‐toxic agents that target intracellular signalling pathways in apoptosis may have
potential therapeutic use in many diseases. One such agent is the transition metal Zn, a …

Apoptosis is a type of cell death involved in several biological events during tissue
development, remodelling or involution. It could be induced by several extracellular or …

OBJECTIVE: The present study examined the effect of zinc at concentrations of the apoptotic
signaling pathway and immune function of peripheral blood mononuclear cells (PBMCs) …