ReP USP - Detalhe do registro: A randomized, double-blind, placebo-controlled trial of creatine
monohydrate as adjunctive treatment for bipolar depression Home About USP Schools USP …

Depressive episodes are a major cause of morbidity and dysfunction in individuals suffering
from bipolar disorder. Currently available treatments for this condition have limited efficacy …

Objectives: Creatine plays a pivotal role in brain energy homeostasis, and altered cerebral
energy metabolism may be involved in the pathophysiology of depression. Oral creatine …

Os episódios depressivos constituem a principal causa de morbidade e disfuncionalidade
para indivíduos acometidos de transtorno bipolar (TB) ao longo do curso da doença. Os …

Background Depressive episodes and cognitive impairment are major causes of morbidity
and dysfunction in individuals suffering from bipolar disorder (BD). Novel treatment …

Creatine's effects on brain energy metabolism raise the possibility of developing a new
therapeutic strategy in depression focusing on the treatment of metabolic hypoactive brain …

Bipolar disorder (BD) type I is a condition that affects approximately 1% of the worlds
population, characterized by chronic periods of manic mood fluctuating between depression …

Depression is a common mood disorder associated with high rates of morbidity and mortality
and characterized by a broad range of symptoms, including altered mood and cognitive …

Objective Antidepressants targeting monoaminergic neurotransmitter systems, despite their
immediate effects at the synaptic level, usually require several weeks of administration to …

Objective: Creatine plays a pivotal role in brain energy homeostasis and has been tried in
the treatment of neurologic, neuromuscular, and atherosclerotic disease with a paucity of …