Field strength and potentially scan quality influence brain age estimates

M Korbmacher, M Wang, R Eikeland, R Buchert… - 2023 - hvlopen.brage.unit.no
Background: Brain age is a promising biomarker of brain or general health. However, to
extend the metric's clinical applications, the large intra-individual varibility in age predictions …

Considerations on brain age predictions from repeatedly sampled data across time

M Korbmacher, MY Wang, R Eikeland… - Brain and …, 2023 - Wiley Online Library
Introduction Brain age, the estimation of a person's age from magnetic resonance imaging
(MRI) parameters, has been used as a general indicator of health. The marker requires …

Estimating brain age based on a healthy population with deep learning and structural MRI

X Feng, ZC Lipton, J Yang, SA Small… - arXiv preprint arXiv …, 2019 - arxiv.org
Numerous studies have established that estimated brain age, as derived from statistical
models trained on healthy populations, constitutes a valuable biomarker that is predictive of …

Estimating brain age based on a uniform healthy population with deep learning and structural magnetic resonance imaging

X Feng, ZC Lipton, J Yang, SA Small… - Neurobiology of …, 2020 - Elsevier
Numerous studies have established that estimated brain age constitutes a valuable
biomarker that is predictive of cognitive decline and various neurological diseases. In this …

MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14 468 individuals worldwide

VM Bashyam, G Erus, J Doshi, M Habes, IM Nasrallah… - Brain, 2020 - academic.oup.com
Deep learning has emerged as a powerful approach to constructing imaging signatures of
normal brain ageing as well as of various neuropathological processes associated with …

Probing multiple algorithms to calculate brain age: Examining reliability, relations with demographics, and predictive power

E Bacas, I Kahhalé, PR Raamana… - Human Brain …, 2023 - Wiley Online Library
The calculation of so‐called “brain age” from structural MRIs has been an emerging
biomarker in aging research. Data suggests that discrepancies between chronological age …

BASE: brain age standardized evaluation

L Dular, Ž Špiclin… - NeuroImage, 2024 - Elsevier
Brain age, most commonly inferred from T1-weighted magnetic resonance images (T1w
MRI), is a robust biomarker of brain health and related diseases. Superior accuracy in brain …

[HTML][HTML] Deep neural networks learn general and clinically relevant representations of the ageing brain

EH Leonardsen, H Peng, T Kaufmann, I Agartz… - NeuroImage, 2022 - Elsevier
The discrepancy between chronological age and the apparent age of the brain based on
neuroimaging data—the brain age delta—has emerged as a reliable marker of brain health …

[HTML][HTML] Feasibility of brain age predictions from clinical T1-weighted MRIs

PA Valdes-Hernandez, CL Nodarse, JH Cole… - Brain Research …, 2023 - Elsevier
An individual's brain predicted age minus chronological age (brain-PAD) obtained from
MRIs could become a biomarker of disease in research studies. However, brain age reports …

[PDF][PDF] Towards the Interpretability of Deep Learning Models for Human Neuroimaging

R Müller, A Villringer, W Samek, AV Witte - researchgate.net
Brain-age (BA) estimates based on deep learning are increasingly used as neuroimaging
biomarker for brain health; however, the underlying neural features have remained unclear …