[HTML][HTML] Pulmonary delivery of biological drugs

W Liang, HW Pan, D Vllasaliu, JKW Lam - Pharmaceutics, 2020 - mdpi.com
In the last decade, biological drugs have rapidly proliferated and have now become an
important therapeutic modality. This is because of their high potency, high specificity and …

Pulmonary drug delivery strategies: A concise, systematic review

JS Patil, S Sarasija - Lung India, 2012 - journals.lww.com
Because of limitations associated with the conventional treatment of various chronic
diseases a growing attention has been given to the development of targeted drug delivery …

Clinical perspectives on pulmonary systemic and macromolecular delivery

G Scheuch, MJ Kohlhaeufl, P Brand… - Advanced drug delivery …, 2006 - Elsevier
The large epithelial surface area, the high organ vascularization, the thin nature of the
alveolar epithelium and the immense capacity for solute exchange are factors that led the …

[HTML][HTML] Oral inhalation for delivery of proteins and peptides to the lungs

E Fröhlich, S Salar-Behzadi - European Journal of Pharmaceutics and …, 2021 - Elsevier
Oral inhalation is the preferred route for delivery of small molecules to the lungs, because
high tissue levels can be achieved shortly after application. Biologics are mainly …

Pulmonary drug delivery. Part II: the role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medications

NR Labiris, MB Dolovich - British journal of clinical …, 2003 - Wiley Online Library
Research in the area of pulmonary drug delivery has gathered momentum in the last several
years, with increased interest in using the lung as a means of delivering drugs systemically …

The ascent of pulmonary drug delivery

I Gonda - Journal of pharmaceutical sciences, 2000 - Elsevier
The origins of inhalation therapy can be traced back to the early civilizations but this route of
administration was relatively uncommon until recently. Direct delivery of drugs to the lung by …

Pulmonary drug delivery: physiologic and mechanistic aspects

J Yu, YW Chien - Critical Reviews™ in Therapeutic Drug …, 1997 - dl.begellhouse.com
Peptide and protein drugs are being used increasingly in major research and development
programs in the pharmaceutical industry and are also an important class of therapeutic …

Drug delivery to the lungs: Challenges and opportunities

SP Newman - Therapeutic delivery, 2017 - Taylor & Francis
Pulmonary drug delivery is relatively complex because the respiratory tract has evolved
defense mechanisms to keep inhaled drug particles out of the lungs and to remove or …

Pulmonary drug delivery systems: recent developments and prospects

HM Courrier, N Butz… - Critical Reviews™ in …, 2002 - dl.begellhouse.com
Targeting drug delivery into the lungs has become one of the most important aspects of
systemic or local drug delivery systems. Consequently, in the last few years, techniques and …

Protein and peptide delivery to lungs by using advanced targeted drug delivery

DK Chellappan, P Prasher, V Saravanan… - Chemico-biological …, 2022 - Elsevier
The challenges and difficulties associated with conventional drug delivery systems have led
to the emergence of novel, advanced targeted drug delivery systems. Therapeutic drug …