Estrogens play a crucial physiological function in the brain; however, debates exist
concerning the role of estrogens in Alzheimer's disease (AD). Women during pre-, peri-, or …

The female sex hormone estrogen has been ascribed potent neuroprotective properties. It
signals by binding and activating estrogen receptors that, depending on receptor subtype …

Alzheimer's disease (AD) is one of the most common types of dementia among the aged
population, with a higher prevalence in women. The reason for this latter observation …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
memory loss and disordered cognition. Women have a higher AD incidence than men …

Estrogen plays key regulatory roles in a variety of biological actions besides its classic
function as a sex hormone. Recently, estrogen has been linked to neurodegenerative …

The results of recent clinical studies have challenged our previously held view that estrogen
therapy promotes neurological health and prevents or ameliorates Alzheimer's disease. A …

Considerable evidence has emerged through more than a decade of research supporting
the neuroprotective and cognition-preserving effects of estrogens. Such basic research …

Risk for Alzheimer's disease (AD) is associated with age-related loss of sex steroid
hormones in both women and men. In post-menopausal women, the precipitous depletion of …

Estrogens are the primary female sex hormones and play important roles in both
reproductive and non-reproductive systems. Estrogens can be synthesized in non …

Alzheimer's disease (AD) disproportionally affects women and men. The female
susceptibility for AD has been largely associated with the loss of ovarian sex hormones …