Early evolution of conserved regulatory sequences associated with development in vertebrates
Comparisons between diverse vertebrate genomes have uncovered thousands of highly
conserved non-coding sequences, an increasing number of which have been shown to …
conserved non-coding sequences, an increasing number of which have been shown to …
A reporter assay in lamprey embryos reveals both functional conservation and elaboration of vertebrate enhancers
The sea lamprey is an important model organism for investigating the evolutionary origins of
vertebrates. As more vertebrate genome sequences are obtained, evolutionary …
vertebrates. As more vertebrate genome sequences are obtained, evolutionary …
[HTML][HTML] Systematic human/zebrafish comparative identification of cis-regulatory activity around vertebrate developmental transcription factor genes
Pan-vertebrate developmental cis-regulatory elements are discernible as highly conserved
noncoding elements (HCNEs) and are often dispersed over large areas around the …
noncoding elements (HCNEs) and are often dispersed over large areas around the …
Functional genetic analysis in a jawless vertebrate, the sea lamprey: insights into the developmental evolution of early vertebrates
JR York, DW McCauley - Journal of Experimental Biology, 2020 - journals.biologists.com
Lampreys and hagfishes are the only surviving relicts of an ancient but ecologically
dominant group of jawless fishes that evolved in the seas of the Cambrian era over half a …
dominant group of jawless fishes that evolved in the seas of the Cambrian era over half a …
New technologies, new findings, and new concepts in the study of vertebrate cis‐regulatory sequences
JL Gómez‐Skarmeta, B Lenhard… - … dynamics: an official …, 2006 - Wiley Online Library
All vertebrates share a similar early embryonic body plan and use the same regulatory
genes for their development. The availability of numerous sequenced vertebrate genomes …
genes for their development. The availability of numerous sequenced vertebrate genomes …
CONDOR: a database resource of developmentally associated conserved non-coding elements
Background Comparative genomics is currently one of the most popular approaches to
study the regulatory architecture of vertebrate genomes. Fish-mammal genomic …
study the regulatory architecture of vertebrate genomes. Fish-mammal genomic …
Developmental mechanisms and cis-regulatory codes
A Ochoa-Espinosa, S Small - Current opinion in genetics & development, 2006 - Elsevier
Complex networks of transcriptional interactions control the processes of animal
development. These networks begin with broad positional information that patterns the cells …
development. These networks begin with broad positional information that patterns the cells …
Shuffling of cis-regulatory elements is a pervasive feature of the vertebrate lineage
R Sanges, E Kalmar, P Claudiani, M D'Amato, F Muller… - Genome biology, 2006 - Springer
Background All vertebrates share a remarkable degree of similarity in their development as
well as in the basic functions of their cells. Despite this, attempts at unearthing genome-wide …
well as in the basic functions of their cells. Despite this, attempts at unearthing genome-wide …
The importance of being cis: evolution of orthologous fish and mammalian enhancer activity
Conserved noncoding elements (CNEs) in vertebrate genomes often act as developmental
enhancers, but a critical issue is how well orthologous CNE sequences retain the same …
enhancers, but a critical issue is how well orthologous CNE sequences retain the same …
DNA conserved in diverse animals since the Precambrian controls genes for embryonic development
DNA that controls gene expression (eg enhancers, promoters) has seemed almost never to
be conserved between distantly related animals, like vertebrates and arthropods. This is …
be conserved between distantly related animals, like vertebrates and arthropods. This is …