Monocytes/macrophages are key players in all phases of physiological and pathological
inflammation. To understanding the regulation of macrophage functional differentiation …

Monocytes and macrophages have a central role in all phases of an inflammatory reaction.
To understanding the regulation of monocyte activation during a physiological or …

Macrophages are dynamic cells integrating signals from their microenvironment to develop
specific functional responses. Although, microarray-based transcriptional profiling has …

Redefining inflammatory macrophage phenotypes across stages and tissues by single-cell
transcriptomics | Science Immunology news careers commentary Journals Science Science …

Macrophages are heterogeneous leukocytes regulated in a tissue-and disease-specific
context. While in vitro macrophage models have been used to study diseases empirically, a …

Growing evidence defines macrophages (Mφ) as plastic cells with wide-ranging states of
activation and expression of different markers that are time and location dependent. Distinct …

Macrophages are cells with remarkable plasticity. They integrate signals from their
microenvironment leading to context-dependent polarization into classically (M1) or …

Monocytes recruited into tissues from peripheral blood differentiate into macrophages, which
are critical in the pathogenesis of many diseases. There is limited data concerning the …

Tissue macrophages play a key role in many aspects of human physiology and pathology.
These cells are heterogeneous both in term of morphology and function. As an example …

Macrophage activation is associated with profound transcriptional reprogramming. Although
much progress has been made in the understanding of macrophage activation, polarization …