Immunotherapy is an emerging form of cancer therapy that is associated with promising
outcomes. However, most cancer patients either do not respond to immunotherapy or …

Use of immunotherapy in recent years has revolutionized cancer treatment for certain types
of cancers. However, the broad utility of immunotherapy is limited because there are still …

Although the introduction of immunotherapy has tremendously improved the prognosis of
patients with metastatic cancers of different histological origins, some tumors fail to respond …

Tumor recurrence and drug resistance are two of the key factors affecting the prognosis of
cancer patients. Cancer stem cells (CSCs) are a group of cells with infinite proliferation …

Resistance to tumor therapy is an unsolved problem in cancer treatment. A plethora of
studies have attempted to explain this phenomenon and many mechanisms of resistance …

Cancer stem cells (CSCs) are correlated with poor clinical outcomes due to their contribution
to chemotherapy resistance and the formation of metastasis. Multiple cell surface and …

Introduction: Conventional chemotherapies seemed to have reached a therapeutic plateau
in the treatment of solid tumors and many metastatic diseases are still incurable. Events of …

Cancer stem cells or cancer-initiating cells (CSCs/CICs) represent a rare population within
tumor lesions that are responsible for tumor formation, progression, and resistance to …

Failure of treatment strategies against cancers is a major issue engaging many scientists to
investigate the possible resistance factors. Cancer stem cells (CSCs) subvert promising …

Cancer stem cells (CSCs), the tumor-initiating cells playing a crucial role in cancer
progression, recurrence, and metastasis, have the intrinsic property of self-renewal and …