Introduction Dementia is a progressive neurodegenerative disorder impairing memory and
cognition. Alzheimer's Disease, followed by vascular dementia–the most typical form. Risk …

There is increasing evidence linking cholesterol metabolism with the neurofibrillary
pathology of Alzheimer's disease (AD). Cholesterol and its transport have been shown to be …

Evidences from cell culture experiments and animal studies suggest a strong link between
cholesterol and Alzheimer's disease (AD). This relationship is supported by retrospective …

Cholesterol, its catabolites and proteins that regulate cholesterol levels all modulate
processing of amyloid precursor protein. Statins hold promise in therapy of Alzheimer's …

Experimental in vitro and in vivo findings as well as some retrospective epidemiological
studies link cholesterol homeostasis with Alzheimer's disease (AD), and there are some …

The link between cholesterol and Alzheimer's disease (AD) is indicated by genetic,
epidemiological, experimental and clinical evidence, although the relationship is far from …

Alzheimer's Disease (AD) is the most common neurodegenerative disorder in western
societies affecting up to 15 million individuals worldwide. It leads to death after a progressive …

Disease-modifying therapies are being developed for Alzheimer's disease (AD). These are
expected to slow the clinical progression of the disease or delay its onset. Cerebral …

Several lines of evidences support a possible involvement of serum cholesterol in the
development of dementia/Alzheimer's disease (AD), with hypercholesterolemia as one of the …

Evaluation of: Sano M, Bell KL, Galasko D et al. A randomized, double-blind, placebo-
controlled trial of simvastatin to treat Alzheimer disease. Neurology 77 (6), 556–563 (2011) …