Background Modern genotyping platforms permit a systematic search for inherited
components of complex diseases. We performed a joint analysis of two genomewide …

In this review, we summarize current knowledge on the genetics of coronary artery disease,
based on 10 years of genome-wide association studies. The discoveries began with …

Background—Combined analysis of 2 genome-wide association studies in cases enriched
for family history recently identified 7 loci (on 1p13. 3, 1q41, 2q36. 3, 6q25. 1, 9p21, 10q11 …

Background: Genome-wide association studies provided many biological insights into
coronary artery disease (CAD), but these studies were mainly performed in Europeans …

Coronary artery disease (CAD) is the commonest cause of death. Here, we report an
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …

Aims Recent genome-wide association (GWA) studies identified 10 chromosomal loci for
coronary artery disease (CAD) or myocardial infarction (MI). However, these loci explain …

Background—Recent genome-wide association studies (GWAS) of myocardial infarction
(MI) and other forms of coronary artery disease (CAD) have led to the discovery of at least 13 …

The discovery of genetic loci associated with complex diseases has outpaced the
elucidation of mechanisms of disease pathogenesis. Here we conducted a genome-wide …

Purpose: Because multiple genetic variants influence risk for coronary heart disease, we
combined multiple variants that had been associated with coronary heart disease in several …

Background: Genome-wide association studies have so far identified 56 loci associated with
risk of coronary artery disease (CAD). Many CAD loci show pleiotropy; that is, they are also …