Network analysis of symptom comorbidity in schizophrenia: relationship to illness course and brain white matter microstructure

H Ye, A Zalesky, J Lv, SM Loi… - Schizophrenia …, 2021 - academic.oup.com
Introduction Recent network-based analyses suggest that schizophrenia symptoms are
intricately connected and interdependent, such that central symptoms can activate adjacent …

Connectome-based patterns of first-episode medication-naive patients with schizophrenia

LB Cui, Y Wei, YB Xi, A Griffa, SC De Lange… - Schizophrenia …, 2019 - academic.oup.com
Emerging evidence indicates that a disruption in brain network organization may play an
important role in the pathophysiology of schizophrenia. The neuroimaging fingerprint …

Distinguishable brain networks relate disease susceptibility to symptom expression in schizophrenia

Z Liu, J Zhang, K Zhang, J Zhang, X Li… - Human brain …, 2018 - Wiley Online Library
Disease association studies have characterized altered resting‐state functional
connectivities describing schizophrenia, but failed to model symptom expression well. We …

Altered white matter connectivity within and between networks in antipsychotic-naive first-episode schizophrenia

F Li, S Lui, L Yao, GJ Ji, W Liao… - Schizophrenia …, 2018 - academic.oup.com
Analyzing the schizophrenia connectome can identify illness-related alterations in
connectivity across the brain. An important question that remains unanswered is whether …

Structural covariance networks in schizophrenia: A systematic review Part II

K Prasad, J Rubin, A Mitra, M Lewis, N Theis… - Schizophrenia …, 2022 - Elsevier
Background Examination of structural covariance network (SCN) is gaining prominence
among the strategies to delineate dysconnectivity that case-control morphometric …

Variable global dysconnectivity and individual differences in schizophrenia

MW Cole, A Anticevic, G Repovs, D Barch - Biological psychiatry, 2011 - Elsevier
Background A fundamental challenge for understanding neuropsychiatric disease is
identifying sources of individual differences in psychopathology, especially when there is …

Further neuroimaging evidence for the deficit subtype of schizophrenia: a cortical connectomics analysis

AL Wheeler, M Wessa, PR Szeszko, G Foussias… - JAMA …, 2015 - jamanetwork.com
Importance The clinical heterogeneity of schizophrenia has hindered neurobiological
investigations aimed at identifying neural correlates of the disorder. Objective To identify …

Interindividual variability of functional connectome in schizophrenia

A Santo-Angles, R Salvador, JJ Gomar… - Schizophrenia …, 2021 - Elsevier
Schizophrenia is a complex psychiatric disorder that displays an outstanding interindividual
variability in clinical manifestation and neurobiological substrates. A better characterization …

Fibre density and fibre-bundle cross-section of the corticospinal tract are distinctly linked to psychosis-specific symptoms in antipsychotic-naïve patients with first …

TD Kristensen, JM Raghava, MW Skjerbæk… - European Archives of …, 2023 - Springer
Multiple lines of research support the dysconnectivity hypothesis of schizophrenia. However,
findings on white matter (WM) alterations in patients with schizophrenia are widespread and …

Connectome organization is related to longitudinal changes in general functioning, symptoms and IQ in chronic schizophrenia

G Collin, J de Nijs, HEH Pol, W Cahn… - Schizophrenia …, 2016 - Elsevier
Emerging evidence suggests schizophrenia to involve widespread alterations in the
macroscale wiring architecture of the human connectome. Recent findings of attenuated …