New look to an old symptom: angina pectoris

F Crea, A Gaspardone - Circulation, 1997 - Am Heart Assoc
At the turn of this century, it was proposed that ischemic cardiac pain might be related to
distension of the ventricular wall (“mechanical hypothesis”). Three decades later, it was …

Mechanisms of pain in angina pectoris—a critical review of the adenosine hypothesis

C Sylvén - Cardiovascular drugs and therapy, 1993 - Springer
Clinical characteristics: Angina pectoris represents a visceral pain caused by reversible
myocardial ischemia. The majority of ischemic attacks are symptomless. When pain is …

Relation between stimulation site of cardiac afferent nerves by adenosine and distribution of cardiac pain: results of a study in patients with stable angina

F Crea, A Gaspardone, JC Kaski, G Davies… - Journal of the American …, 1992 - Elsevier
Objectives. The purpose of this study was to establish whether stimulation of cardiac sensory
receptors in different myocardial regions results in different distributions of cardiac pain …

Adenosine-provoked angina pectoris-like pain—time characteristics, influence of autonomic blockade and naloxone

C Sylvén, B Jonzon, R Brandt… - European Heart …, 1987 - academic.oup.com
In a study to characterize the time characteristics and the influence of blockade of beta,
cholinergic and opioid receptors on the chest pain induced by adenosine, this agent was …

The brain-heart axis in the perception of cardiac pain: the elusive link between ischaemia and pain

SD Rosen, PG Camici - Annals of medicine, 2000 - Taylor & Francis
Angina pectoris is a common symptom and one that can have profound implications for the
patient. However, it correlates poorly with the extent of myocardial ischaemia and with …

Mechanisms and significance of cardiac ischemic pain

A Maseri, F Crea, JC Kaski, G Davies - Progress in cardiovascular diseases, 1992 - Elsevier
Anginal PAIN is the symptom that most often brings patients with ischemic heart disease to
medical attention. However, transient myocardial ischemia and even necrosis can occur …

Intracoronary adenosine causes angina pectoris like pain–an inquiry into the nature of visceral pain

B Lagerqvist, C Sylvén, B Beermann… - Cardiovascular …, 1990 - academic.oup.com
Study objective–The aim was to study the tentative role of adenosine as a messenger
between myocardial ischaemia and angina pectoris. Design–Adenosine was administered …

Neurophysiological aspects of angina pectoris.

C Sylven - Zeitschrift fur Kardiologie, 1997 - europepmc.org
Several clinical characteristics of angina pectoris are reflected in the nature of the cardiac
nervous system. The extent of silent ischemia, the slow onset of angina during the ischemic …

From heart to brain: the genesis and processing of cardiac pain

SD Rosen - Canadian Journal of Cardiology, 2012 - Elsevier
Angina pectoris is important because of its association with heart disease and risk of death.
Historically after Heberden's account of angina in 1772, the association of pain with …

Pathophysiology of cardiac pain

R Gorlin - Circulation, 1965 - Am Heart Assoc
ANGINA pectoris can be no better described than in Heberden's original discussion some
160 years ago.'Despite the enduring quality of his description, Heberden had no idea of the …