Severity of individual obstruction events is gender dependent in sleep apnea

T Leppänen, A Kulkas, B Duce, E Mervaala… - Sleep and Breathing, 2017 - Springer
Purpose In obstructive sleep apnea (OSA), severity of individual obstruction events is
connected to increased mortality rate and it can be significantly different in patients with …

Severity of individual obstruction events increases with age in patients with obstructive sleep apnea

T Leppänen, J Töyräs, E Mervaala, T Penzel, A Kulkas - Sleep medicine, 2017 - Elsevier
Background Age is a risk factor of obstructive sleep apnea (OSA). It has been shown that
OSA progresses over time, although conflicting results have been reported. However, the …

The severity of individual obstruction events is related to increased mortality rate in severe obstructive sleep apnea

A Muraja‐Murro, A Kulkas, M Hiltunen… - Journal of Sleep …, 2013 - Wiley Online Library
Obstructive sleep apnea (OSA) is linked to an increased mortality rate. However, the severity
of individual obstruction events is rarely considered quantitatively in clinical practice. We …

Adjustment of apnea-hypopnea index with severity of obstruction events enhances detection of sleep apnea patients with the highest risk of severe health …

A Muraja-Murro, A Kulkas, M Hiltunen, S Kupari… - Sleep and …, 2014 - Springer
Introduction Presently, the severity of obstructive sleep apnea (OSA) is estimated based on
the apnea-hypopnea index (AHI). Unfortunately, AHI does not provide information on the …

Severity of desaturations reflects OSA-related daytime sleepiness better than AHI

S Kainulainen, J Töyräs, A Oksenberg… - Journal of Clinical …, 2019 - jcsm.aasm.org
Study Objectives: The aim was to investigate how the severity of apneas, hypopneas, and
related desaturations is associated with obstructive sleep apnea (OSA)-related daytime …

Hypoxemic features of obstructive sleep apnea and the risk of mortality: a cluster analysis

G Labarca, J Jorquera, J Dreyse, C Salas… - Sleep and Breathing, 2021 - Springer
Introduction Patients with moderate to severe obstructive sleep apnea (OSA) have an
increased risk of cardiovascular comorbidities and mortality. Although different subtypes of …

Time under 90% oxygen saturation and systemic hypertension in patients with obstructive sleep apnea syndrome

L Wang, D Wei, J Zhang, J Cao - Nature and science of sleep, 2022 - Taylor & Francis
Purpose The diagnosis and severity of obstructive sleep apnea (OSA) are commonly based
on the apnea hypopnea index (AHI). However, patients with similar severity AHIs may show …

Differences in arousal probability and duration after apnea and hypopnea events in adult obstructive sleep apnea patients

T Leppänen, A Kulkas, A Oksenberg… - Physiological …, 2018 - iopscience.iop.org
Objective: In obstructive sleep apnea (OSA), breathing cessations are often followed by
arousals, leading to sleep fragmentation and thus impaired sleep quality. Arousals and …

The impact of sleep duration in obstructive sleep apnea patients

TT Risso, D Poyares, CF Rizzi, C Pulz… - Sleep and …, 2013 - Springer
Purpose Obstructive sleep apnea (OSA) is a risk factor for cardiovascular disease. Strong
associations have been reported among sleep duration, hypertension, obesity, and …

Increase in body mass index decreases duration of apneas and hypopneas in obstructive sleep apnea

T Leppänen, A Kulkas, E Mervaala, J Töyräs - Respiratory care, 2019 - rc.rcjournal.com
BACKGROUND: Obesity is one of the most prominent risk factors for obstructive sleep
apnea (OSA). Weight loss decreases the number of shorter respiratory events (< 40 s) …