Type 2B von Willebrand disease (VWD2B) is caused by an abnormal von Willebrand factor
(VWF) with increased affinity for the platelet receptor glycoprotein Ib-α (GPIb-α) that may …

Background: Type 2A and 2M von Willebrand disease (VWD2A and VWD2M) are
characterized by the presence of a dysfunctional von Willebrand factor (VWF) and a variable …

Summary Background Type 3 von Willebrand disease (VWD) is the most severe form of the
disease and is classically inherited in an autosomal recessive fashion. Objectives The aim of …

Type 2B von Willebrand disease (VWD) is an inherited bleeding disorder caused by
changes in von Willebrand factor (VWF) that enhance binding of VWF to GPIb on platelets …

von Willebrand disease type 2B (vWD-type 2B) is characterized by gain-of-function
mutations in von Willebrand factor (vWF) that enhance its binding to the glycoprotein Ib-IX-V …

Platelet-type von Willebrand disease (PT-VWD) and type 2B von Willebrand disease (2B-
VWD) have different etiologies although both present with a similar clinical bleeding and …

Forty families diagnosed by UK centres to have type 1 VWD were recruited. Following
review, six families were re-diagnosed to have type 2 VWD, one to have a platelet storage …

The online locus-specific database for von Willebrand disease (VWFdb) acts as a repository
for sequence variant data and associated resources for those with an interest in the disorder …

Summary Background: Candidate von Willebrand factor (VWF) mutations were identified in
70% of index cases in the European study 'Molecular and Clinical Markers for the Diagnosis …

In order to evaluate the changes within the VWF gene that might contribute to the
pathogenesis of type 1 von Willebrand disease (VWD), a large multicenter Canadian study …