Chronic alcohol exposure reduces hippocampal neurogenesis and dendritic growth of newborn neurons

J He, K Nixon, AK Shetty… - European Journal of …, 2005 - Wiley Online Library
Hippocampal neurogenesis is known as the formation of new neurons from the proliferating
neural progenitor cells (NPC) at the dentate gyrus. Cell proliferation, survival, differentiation …

Alcohol inhibition of neurogenesis: a mechanism of hippocampal neurodegeneration in an adolescent alcohol abuse model

SA Morris, DW Eaves, AR Smith, K Nixon - Hippocampus, 2010 - Wiley Online Library
Adolescents diagnosed with an alcohol use disorder show neurodegeneration in the
hippocampus, a region important for learning, memory, and mood regulation. This study …

Chronic alcohol exposure is associated with decreased neurogenesis, aberrant integration of newborn neurons, and cognitive dysfunction in female mice

HM Golub, QG Zhou, H Zucker… - Alcoholism: Clinical …, 2015 - Wiley Online Library
Background Neurological deficits of alcohol use disorder (AUD) have been attributed to
dysfunctions of specific brain structures. Studies of alcoholic patients and chronic alcohol …

Impact of exercise and a complex environment on hippocampal dendritic morphology, Bdnf gene expression, and DNA methylation in male rat pups neonatally …

KE Boschen, SE McKeown, TL Roth… - Developmental …, 2017 - Wiley Online Library
Alcohol exposure in utero can result in Fetal Alcohol Spectrums Disorders (FASD).
Measures of hippocampal neuroplasticity, including long‐term potentiation, synaptic and …

Adolescent binge alcohol exposure alters hippocampal progenitor cell proliferation in rats: effects on cell cycle kinetics

JA McClain, DM Hayes, SA Morris… - Journal of Comparative …, 2011 - Wiley Online Library
Binge alcohol exposure in adolescent rats potently inhibits adult hippocampal neurogenesis
by altering neural progenitor cell (NPC) proliferation and survival; however, it is not clear …

Persistent decreases in adult subventricular and hippocampal neurogenesis following adolescent intermittent ethanol exposure

W Liu, FT Crews - Frontiers in behavioral neuroscience, 2017 - frontiersin.org
Neurogenesis in hippocampal dentate gyrus (DG) and subventricular zone (SVZ) matures
during adolescence to adult levels. Binge drinking is prevalent in adolescent humans, and …

Long-lasting reduction in hippocampal neurogenesis by alcohol consumption in adolescent nonhuman primates

MA Taffe, RW Kotzebue, RD Crean… - Proceedings of the …, 2010 - National Acad Sciences
Binge alcohol consumption in adolescents is increasing, and studies in animal models show
that adolescence is a period of high vulnerability to brain insults. The purpose of the present …

Persistent impairment of hippocampal neurogenesis in young adult rats following early postnatal alcohol exposure

AY Klintsova, JL Helfer, LH Calizo… - Alcoholism: Clinical …, 2007 - Wiley Online Library
Background: Prenatal alcohol exposure can cause damage to the developing fetus with
outcomes including growth deficiency, facial dysmorphology, brain damage, and cognitive …

Roles of neural stem cells and adult neurogenesis in adolescent alcohol use disorders

K Nixon, SA Morris, DJ Liput, ML Kelso - Alcohol, 2010 - Elsevier
This review discusses the contributions of a newly considered form of plasticity, the ongoing
production of new neurons from neural stem cells, or adult neurogenesis, within the context …

Binge ethanol exposure during adolescence leads to a persistent loss of neurogenesis in the dorsal and ventral hippocampus that is associated with impaired adult …

RP Vetreno, FT Crews - Frontiers in neuroscience, 2015 - frontiersin.org
Adolescence is a developmental period that coincides with the maturation of adult cognitive
faculties. Binge drinking is common during adolescence and can impact brain maturation …