The use of collision cross-section (CCS) values derived from ion mobility–mass
spectrometry (IM–MS) has been proven to facilitate lipid identifications. Its utility is restricted …

Despite recent advances in analytical and computational chemistry, lipid identification
remains a significant challenge in lipidomics. Ion-mobility spectrometry provides an accurate …

Ion mobility—mass spectrometry (IM-MS) has showed great application potential for
lipidomics. However, IM-MS based lipidomics is significantly restricted by the available …

Comprehensive profiling of lipid species in a biological sample, or lipidomics, is a valuable
approach to elucidating disease pathogenesis and identifying biomarkers. Currently, a …

Highlights•Ion mobility–mass spectrometry (IM–MS) supports the metabolomics and
lipidomics applications.•Collision cross-section (CCS) value is a valuable physiochemical …

Structures for lossless ion manipulation-based high-resolution ion mobility (HRIM) interfaced
with mass spectrometry has emerged as a powerful tool for the separation and analysis of …

The development of ion mobility–mass spectrometry (IM–MS) has revolutionized the
analysis of small molecules, such as metabolomics, lipidomics, and exposome studies. The …

Lipids represent an important class of biomolecules, and play numerous roles in
physiological and pathological processes and activates. The enormous chemical and …

Identification of unknowns is a bottleneck for large-scale untargeted analyses like
metabolomics or drug metabolite identification. Ion mobility-mass spectrometry (IM-MS) …

Collision cross section (CCS) measurement of lipids using traveling wave ion mobility-mass
spectrometry (TWIM-MS) is of high interest to the lipidomics field. However, currently …